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anti-IL3 antibody :: Mouse anti-Human IL3 Monoclonal Antibody

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Catalog # MBS531529
Unit / Price
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  0.25 mg  /  $160 +1 FREE 8GB USB
anti-IL3 antibody
Product Name

IL3, Monoclonal Antibody

Full Product Name

IL3 antibody

Product Synonym Names
Monoclonal IL3; Anti-IL3; IL 3; IL-3; Interleukin-3; IL3
Product Gene Name
Matching Pairs
Capture Antibody: IL3 Clone #M313121 (MBS531529)
Detection Antibody: IL3 Clone #M313122 (MBS531405)
Comments: For use in sandwich immunoassay
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
147740
3D Structure
ModBase 3D Structure for P08700
Clonality
Monoclonal
Isotype
IgG1
Clone Number
M313121
Host
Mouse
Species Reactivity
Human
Purity/Purification
IL3 antibody was purified by chromatography on protein G Sepharose.
Form/Format
Purified murine ascites supplied in PBS, pH 7.2, 0.1 % NaN3.
Biological Significance
Interleukin-3 (IL-3) is an interleukin, a type of biological signal (cytokine) that can improve the body's natural response to disease as part of the immune system. It acts by binding to the interleukin-3 receptor. IL-3 stimulates the differentiation of multipotent hematopoietic stem cells into myeloid progenitor cells as well as stimulates proliferation of all cells in the myeloid lineage.
Biohazard Information
This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen
IL3 antibody was raised in mouse using recombinant human IL-3 as the immunogen.
Preparation and Storage
Store at 4 degree C.
Other Notes
Small volumes of anti-IL3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-IL3 antibody
Mouse monoclonal IL3 antibody
Product Categories/Family for anti-IL3 antibody
Applications Tested/Suitable for anti-IL3 antibody
ELISA (EIA)
Application Notes for anti-IL3 antibody
MBS531529 can be used as the coating antibody along with MBS531405 as the detection antibody
NCBI/Uniprot data below describe general gene information for IL3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
17,233 Da
NCBI Official Full Name
interleukin-3
NCBI Official Synonym Full Names
interleukin 3
NCBI Official Symbol
NCBI Official Synonym Symbols
IL-3; MCGF; MULTI-CSF
  [Similar Products]
NCBI Protein Information
interleukin-3
UniProt Protein Name
Interleukin-3
UniProt Synonym Protein Names
Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
IL-3; MCGF  [Similar Products]
UniProt Entry Name
IL3_HUMAN
NCBI Summary for IL3
The protein encoded by this gene is a potent growth promoting cytokine. This cytokine is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders. [provided by RefSeq, Jul 2008]
UniProt Comments for IL3
IL3: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family.

Protein type: Secreted, signal peptide; Cell cycle regulation; Apoptosis; Oncoprotein; Cytokine; Secreted

Chromosomal Location of Human Ortholog: 5q31.1

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-3 receptor binding; growth factor activity; cytokine activity

Biological Process: nervous system development; positive regulation of peptidyl-tyrosine phosphorylation; cell-cell signaling; positive regulation of tyrosine phosphorylation of Stat5 protein; embryonic hemopoiesis; cytokine and chemokine mediated signaling pathway; positive regulation of cell proliferation; immune response; positive regulation of myeloid leukocyte differentiation; positive regulation of DNA replication
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with anti-IL3 antibody
 Organ/Tissue Name  Pubmed Publications
 Mixed Antibodies  >13 publications with IL3 and Mixed
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