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anti-KCNIP1 antibody :: Mouse anti-Human KCNIP1 Monoclonal Antibody

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Catalog # MBS2517872
Unit / Price
  0.06 mL  /  $220 +1 FREE 8GB USB
  0.12 mL  /  $290 +1 FREE 8GB USB
  0.2 mL  /  $435 +1 FREE 8GB USB
Western Blot (WB)
Product Name

KCNIP1, Monoclonal Antibody

Also Known As

KCNIP1 Monoclonal Antibody

Product Synonym Names
A type potassium channel modulatory protein 1; A-type potassium channel modulatory protein 1; KChIP1; KCIP1; Kcnip1; Kv channel interacting protein 1; Kv channel-interacting protein 1; MGC9; MGC95; Potassium channel interacting protein 1; Potassium channel-interacting protein 1; VABP; Vesicle APC binding protein; Vesicle APC-binding protein
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
227
OMIM
604660 geneneXtProt; the human protein knowledge platformMore
3D Structure
ModBase 3D Structure for Q9NZI2
Clonality
Monoclonal
Isotype
IgG1
Clone Number
3D6C1
Host
Mouse
Species Reactivity
Human
Purity/Purification
Protein G purification
Concentration
1mg/mL (lot specific)
Immunogen
Fusion protein of KChIP1
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-KCNIP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-KCNIP1 antibody
Human K(v) channel interacting protein 1 (KCHIP1) is a new member of the neural calcium binding protein superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. KChIP1 is a neuronal calcium sensor protein that is predominantly expressed at GABAergic synapses and it has been related with modulation of K(+) channels, GABAergic transmission and cell death.
Applications Tested/Suitable for anti-KCNIP1 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-KCNIP1 antibody
WB: 1:1000-1:4000
IHC: 1:50-1:500

Western Blot (WB) of anti-KCNIP1 antibody
Western Blot analysis of Human cerebellum tissue using KChIP1 Monoclonal Antibody at dilution of 1:2000
anti-KCNIP1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for KCNIP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated: 27kDa
Observed: 25kDa
NCBI Official Full Name
Kv channel-interacting protein 1 isoform 1
NCBI Official Synonym Full Names
potassium voltage-gated channel interacting protein 1
NCBI Official Symbol
KCNIP1  [Similar Products]
NCBI Official Synonym Symbols
VABP; KCHIP1
  [Similar Products]
NCBI Protein Information
Kv channel-interacting protein 1
UniProt Protein Name
Kv channel-interacting protein 1
UniProt Synonym Protein Names
A-type potassium channel modulatory protein 1; Potassium channel-interacting protein 1; Vesicle APC-binding protein
UniProt Gene Name
KCNIP1  [Similar Products]
UniProt Synonym Gene Names
KCHIP1; VABP; KChIP1  [Similar Products]
NCBI Summary for KCNIP1
This gene encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the neuronal calcium sensor (NCS) family of the calcium binding EF-hand proteins. They associate with Kv4 alpha subunits to form native Kv4 channel complexes. The encoded protein may regulate rapidly inactivating (A-type) currents, and hence neuronal membrane excitability, in response to changes in the concentration of intracellular calcium. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
UniProt Comments for KCNIP1
Regulatory subunit of Kv4/D (Shal)-type voltage-gated rapidly inactivating A-type potassium channels. Regulates channel density, inactivation kinetics and rate of recovery from inactivation in a calcium-dependent and isoform-specific manner. In vitro, modulates KCND1/Kv4.1 and KCND2/Kv4.2 currents. Increases the presence of KCND2 at the cell surface.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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