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anti-KRT7 antibody :: Mouse anti-Human Keratin 7 Monoclonal Antibody

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Catalog # MBS5306552
Unit / Price
  0.1 mg  /  $430 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Keratin 7 (KRT7), Monoclonal Antibody

Popular Item
Full Product Name

Mouse monoclonal Keratin 7 antibody (N-terminus)

Product Synonym Names
Keratin 7 antibody (N-terminus), Monoclonal Keratin 7 antibody, Anti-Keratin 7 antibody, Cytokeratin 7 antibody, Cytokeratin-7- antibody, Cytokeratin-7 antibody, Keratin K7 antibody, Cytokeratin 7 antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
X03212 mRNA
Clonality
Monoclonal
Isotype
IgG1
Clone Number
M80511
Host
Mouse
Species Reactivity
Human
Specificity
Keratin 7 antibody detects endogenous levels Keratin 7 and does not cross-react with related proteins
Form/Format
Liquid in 0.1M Tris-Glycine, pH 7.4 with 150mM NaCI, 0.2% Sodium Azide, and 50% Glycerol.
Concentration
1 mg/ml (lot specific)
Immunogen
Purified recombinant human Keratin 7 protein fragment expressed in E. coli
Biological Significance
Antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas from colonic and prostate cancers, respectively.
Preparation and Storage
Store at 4°C for short term, -20°C for long term.
Other Notes
Small volumes of anti-KRT7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-KRT7 antibody
Applications Tested/Suitable for anti-KRT7 antibody
Suitable for use in WB and ICC.

Western Blot (WB) of anti-KRT7 antibody
Western blot detection of Keratin 7(N-terminus) antibody in A459&Hela cell lysates using Keratin 7(N-terminus) antibody (1:1000 diluted). Predicted band size: 50KDa Observed band size: 50KDa.
anti-KRT7 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for KRT7. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
keratin 7
NCBI Official Synonym Full Names
keratin 7
NCBI Official Symbol
NCBI Official Synonym Symbols
K7; CK7; SCL; K2C7
  [Similar Products]
NCBI Protein Information
keratin, type II cytoskeletal 7
UniProt Protein Name
Keratin, type II cytoskeletal 7
UniProt Synonym Protein Names
Cytokeratin-7; CK-7; Keratin-7; K7; Sarcolectin; Type-II keratin Kb7
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
SCL; CK-7; K7  [Similar Products]
NCBI Summary for KRT7
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]
UniProt Comments for KRT7
K7: a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Pathways associated with anti-KRT7 antibody
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