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anti-LMNB1 antibody :: Mouse anti-Human Lamin B1 (LMNB1) Monoclonal Antibody

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Catalog # MBS2034696 (SPECIAL PROMOTION: Get FREE $5 Starbucks gift card (Maximum 5 gift cards/product). Gift card(s) will be included with shipment)
Unit / Price
  0.01 mg  /  $100 +1 FREE 8GB USB
  0.02 mg  /  $110 +1 FREE 8GB USB
  0.05 mg  /  $140 +1 FREE 8GB USB
  0.1 mg  /  $175 +1 FREE 8GB USB
  0.2 mg  /  $225 +1 FREE 8GB USB
  1 mg  /  $500 +1 FREE 8GB USB
Western Blot (WB)
Product Name

Lamin B1 (LMNB1), Monoclonal Antibody

Popular Item
Also Known As

Anti-Lamin B1 (LMNB1) Monoclonal Antibody

Product Synonym Names
LMN; LMN2; LMNB
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
APC-CY7 Conjugated Antibody: Lamin B1 (LMNB1) (MBS2076765)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
PE Conjugated Antibody: Lamin B1 (LMNB1) (MBS2076767)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
APC Conjugated Antibody: Lamin B1 (LMNB1) (MBS2076769)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
Cy3 Conjugated Antibody: Lamin B1 (LMNB1) (MBS2076771)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
FITC Conjugated Antibody: Lamin B1 (LMNB1) (MBS2076773)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
HRP Conjugated Antibody: Lamin B1 (LMNB1) (MBS2076775)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
Biotin Conjugated Secondary Antibody: IgG (MBS2086030)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
FITC Conjugated Secondary Antibody: IgG (MBS2086031)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
Biotin Conjugated Secondary Antibody: IgG (MBS2086033)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
FITC Conjugated Secondary Antibody: IgG (MBS2086034)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
HRP Conjugated Secondary Antibody: IgG (MBS2086035)
Matching Pairs
Unconjugated Antibody: Lamin B1 (LMNB1) (MBS2034696)
Biotin Conjugated Antibody: Lamin B1 (LMNB1) (MBS2091231)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
M34458 mRNA
3D Structure
ModBase 3D Structure for P20700
Clonality
Monoclonal
Host
Mouse
Species Reactivity
Human
Specificity
The antibody is a mouse monoclonal antibody raised against LMNB1. It has been selected for its ability to recognize LMNB1 in immunohistochemical staining and western blotting.
Purity/Purification
Protein A + Protein G affinity chromatography
Form/Format
Liquid
Concentration
500ug/ml (lot specific)
Preparation and Storage
Store at 4 degree C for frequent use. Stored at -20 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Other Notes
Small volumes of anti-LMNB1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-LMNB1 antibody
Western Blot (WB)
Application Notes for anti-LMNB1 antibody
Loading Control of WB.

Western Blot (WB) of anti-LMNB1 antibody
Western Blot: Sample: Lane1: Human Lung lysate; Lane2: 293T cell lysate
anti-LMNB1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for LMNB1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
66,408 Da
NCBI Official Full Name
lamin-B1 isoform 1
NCBI Official Synonym Full Names
lamin B1
NCBI Official Symbol
LMNB1  [Similar Products]
NCBI Official Synonym Symbols
LMN; ADLD; LMN2; LMNB
  [Similar Products]
NCBI Protein Information
lamin-B1
UniProt Protein Name
Lamin-B1
Protein Family
UniProt Gene Name
LMNB1  [Similar Products]
UniProt Synonym Gene Names
LMN2; LMNB  [Similar Products]
NCBI Summary for LMNB1
This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
UniProt Comments for LMNB1
Lamin B1: nuclear lamins are intermediate filament proteins that constitute the lattice-like matrix at the inner face of the nuclear membrane that underlies the nuclear envelop. The lamins, highly conserved throughout evolution, are encoded by three genes in the human: LMNA, LMNB1, and LMNB2. The A-type lamins (lamin A/C) are developmentally regulated and are generally expressed in differentiated cells. The anchoring of chromatin to the nuclear lamina is involved in the control of gene expression and in DNA replication and repair. During mitosis, the nuclear lamina is reversibly disassembled as the lamin proteins are phosphorylated. B-type lamins are phosphorylated within minutes of engaging the IgM surface receptor of resting splenic B cells. Nuclear lamins are cleaved by caspases during apoptosis.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 5q23.2

Cellular Component: lamin filament; membrane; nuclear envelope; nuclear inner membrane; nuclear matrix; nuclear membrane; nucleoplasm; nucleus

Molecular Function: phospholipase binding; protein binding; structural molecule activity

Disease: Leukodystrophy, Demyelinating, Adult-onset, Autosomal Dominant
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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