• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-SERPINB5 antibody :: Mouse anti-Human Maspin Monoclonal Antibody

Scan QR to view Datasheet
Catalog # MBS200148
Unit / Price
Scan QR to view Datasheet
  0.05 mL  /  $240 +1 FREE 8GB USB
  0.1 mL  /  $315 +1 FREE 8GB USB
Product Name

Maspin (SERPINB5), Monoclonal Antibody

Full Product Name

Maspin antibody

Product Synonym Names
Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5; Serpin B5; Protease inhibitor 5; SERPINB5; PI5; Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5 Serine (or cysteine) peptidase inhibitor; clade B; member 5; Ovalbumin; PI-5; Serpin peptidase inhibitor; Serpin peptidase inhibitor; clade B (ovalbumin); member 5; SERPINB5; Spi5; Spi7.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
U04313 mRNA
3D Structure
ModBase 3D Structure for P36952
Clonality
Monoclonal
Isotype
IgG2b, k
Clone Number
AT2N6
Host
Mouse
Species Reactivity
Human
Purity/Purification
By protein-G affinity chromatography
Form/Format
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
Concentration
1mg/ml (lot specific)
Antigen Species
Human
Immunogen
Recombinant Maspin (1-375aa) purified from E. coli
Clone Note
Anti-human Maspin mAb, clone AT2N6, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Maspin protein.
Preparation and Storage
Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of anti-SERPINB5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SERPINB5 antibody
Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, also known as Maspin, is a tumor suppressor protein of serine proteinase inhibitor family. It plays an essential role in embryonic development through critical roles in cell adhesion. Also, it is present in normal breast and prostatic epithelial cells but downregulated in the respective carcinomas.
Product Categories/Family for anti-SERPINB5 antibody
Applications Tested/Suitable for anti-SERPINB5 antibody
ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS)
Application Notes for anti-SERPINB5 antibody
WB: 1:1000 ~ 2000.
Recommended starting dilution is 1:1000.

Western Blot (WB) of anti-SERPINB5 antibody
The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human Maspin antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: HeLa cell lysate
anti-SERPINB5 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-SERPINB5 antibody
Immunofluorescence of human HeLa cells stained with PI (Red) and monoclonal anti-Maspin antibody (1:500) with Alexa 488 (Green). ICC/IF analysis of Maspin in HeLa cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human Maspin antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
anti-SERPINB5 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for SERPINB5. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
25,763 Da[Similar Products]
NCBI Official Full Name
serpin B5
NCBI Official Synonym Full Names
serpin family B member 5
NCBI Official Symbol
SERPINB5  [Similar Products]
NCBI Official Synonym Symbols
PI5; maspin
  [Similar Products]
NCBI Protein Information
serpin B5
UniProt Protein Name
Serpin B5
UniProt Synonym Protein Names
Maspin; Peptidase inhibitor 5; PI-5
Protein Family
UniProt Gene Name
SERPINB5  [Similar Products]
UniProt Synonym Gene Names
PI5; PI-5  [Similar Products]
UniProt Comments for SERPINB5
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Product References and Citations for anti-SERPINB5 antibody
Lockett J. et al., (2006) J Cell Biochem 97 (4):651-660; Khalkhali Ellis Z. et al., (2006) Clin Cancer Res 12 (24):7279-7283

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated with anti-SERPINB5 antibody
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000