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anti-MGA antibody :: Mouse anti-Human MGA Monoclonal Antibody

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Catalog # MBS120058
Unit / Price
  0.1 mg  /  $345 +1 FREE 8GB USB
Product Name

MGA, Monoclonal Antibody

Full Product Name

Mouse monoclonal antibody Anti-Human MGA

Product Synonym Names
MAX gene associated; KIAA0518; MAD5; MXD5; FLJ12634
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
616061
Clonality
Monoclonal
Isotype
IgG1
Clone Number
MGA6A4H5
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Other Notes
Small volumes of anti-MGA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-MGA antibody
Dot Blot (DB)

Quality Control of anti-MGA antibody
Western blot analysis of immunized recombinant protein, using anti-MGA monoclonal antibody.
anti-MGA antibody Quality Control image
Quality Control #2 of anti-MGA antibody
Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-MGA antibody Quality Control #2 image
NCBI/Uniprot data below describe general gene information for MGA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
336,159 Da
NCBI Official Full Name
Homo sapiens MAX gene associated, mRNA
NCBI Official Synonym Full Names
MGA, MAX dimerization protein
NCBI Official Symbol
NCBI Official Synonym Symbols
MAD5; MXD5
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NCBI Protein Information
MAX gene-associated protein; MAX dimerization protein 5
UniProt Protein Name
MAX gene-associated protein
UniProt Synonym Protein Names
MAX dimerization protein 5
UniProt Gene Name
UniProt Entry Name
MGAP_HUMAN
UniProt Comments for MGA
MGA iso6: Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor; DNA-binding

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: nucleoplasm; transcription factor complex; cytoplasm

Molecular Function: protein dimerization activity; DNA binding; transcription factor activity

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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