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anti-MUC16 antibody :: Mouse anti-Human MUC16 / CA125 Monoclonal Antibody

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Catalog # MBS245325
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

MUC16 / CA125, Monoclonal Antibody

Full Product Name

Mouse Monoclonal [clone X306] (IgG1) to Human MUC16 / CA125

Product Synonym Names
Anti-MUC16 / CA125 Antibody (clone X306) IHC-plus; MUC16; CA125 ovarian cancer antigen; CA125; CA-125; MUC-16; Mucin-16; Human MUC16; CA125
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
606154
3D Structure
ModBase 3D Structure for Q8WXI7
Clonality
Monoclonal
Isotype
IgG1
Clone Number
X306
Host
Mouse
Species Reactivity
Human
Specificity
CA125 was concluded by the International Society of Oncology and BioMarkers (ISOBM) to contain two major antigenic domains. Recognizes the epitope specificity group A, similar to the OC125 antibody. Not suitable for conjugation to HRP
Purity/Purification
Ion exchange Chromatography
Form/Format
Tris buffered saline, 0.09% sodium azide.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
CA125 antigen purified from human ovarian carcinoma.
Immunogen
MUC16 / CA125 antibody was raised against cA125 antigen purified from human ovarian carcinoma.
Preparation and Storage
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
Other Notes
Small volumes of anti-MUC16 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MUC16 antibody
Also commonly known as Ovarian Cancer Antigen CA-125.
Applications Tested/Suitable for anti-MUC16 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
Application Notes for anti-MUC16 antibody
ELISA, IHC-P (10 ug/ml), WB
Usage: Immunohistochemistry: Validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides...

Immunohistochemistry (IHC) of anti-MUC16 antibody
Anti-MUC16 / CA-125 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-MUC16 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for MUC16. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
2,353,428 Da
NCBI Official Full Name
mucin-16
NCBI Official Synonym Full Names
mucin 16, cell surface associated
NCBI Official Symbol
MUC16  [Similar Products]
NCBI Official Synonym Symbols
CA125
  [Similar Products]
NCBI Protein Information
mucin-16; CA-125; MUC-16; CA125 ovarian cancer antigen; ovarian carcinoma antigen CA125; ovarian cancer-related tumor marker CA125
UniProt Protein Name
Mucin-16
UniProt Synonym Protein Names
Ovarian cancer-related tumor marker CA125; CA-125; Ovarian carcinoma antigen CA125
Protein Family
UniProt Gene Name
MUC16  [Similar Products]
UniProt Synonym Gene Names
CA125; MUC-16; CA-125  [Similar Products]
UniProt Entry Name
MUC16_HUMAN
UniProt Comments for MUC16
MUC16: Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.

Protein type: Membrane protein, integral; Cell adhesion; Membrane protein, peripheral

Chromosomal Location of Human Ortholog: 19p13.2

Cellular Component: extracellular space; extrinsic to membrane; Golgi lumen; integral to membrane; plasma membrane; vesicle

Molecular Function: protein binding

Biological Process: protein amino acid O-linked glycosylation; cellular protein metabolic process; O-glycan processing; post-translational protein modification; cell adhesion
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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