NP_002469.2
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
myoblast determination protein 1
NCBI Official Synonym Full Names
myogenic differentiation 1
NCBI Protein Information
myoblast determination protein 1
UniProt Protein Name
Myoblast determination protein 1
UniProt Synonym Protein Names
Class C basic helix-loop-helix protein 1; bHLHc1; Myogenic factor 3; Myf-3
UniProt Synonym Gene Names
UniProt Entry Name
MYOD1_HUMAN
NCBI Summary for MYOD1
This gene encodes a nuclear protein that belongs to the basic helix-loop-helix family of transcription factors and the myogenic factors subfamily. It regulates muscle cell differentiation by inducing cell cycle arrest, a prerequisite for myogenic initiation. The protein is also involved in muscle regeneration. It activates its own transcription which may stabilize commitment to myogenesis. [provided by RefSeq, Jul 2008]
UniProt Comments for MYOD1
MyoD: a transcription factor of the basic helix-loop-helix family and the myogenic factors subfamily. Involved in muscle differentiation. Induces fibroblasts to differentiate into myoblasts. It is involved in muscle cell differentiation, and is essential for repair of damaged tissue. It activates its own transcription which may stabilize commitment to myogenesis.
Protein type: DNA-binding; RNA splicing; Transcription factor
Chromosomal Location of Human Ortholog: 11p15.4
Cellular Component: cytoplasm; nuclear chromatin; nucleoplasm; nucleus; transcription factor complex
Molecular Function: chromatin binding; chromatin DNA binding; nuclear hormone receptor binding; protein binding; protein heterodimerization activity; RNA polymerase II transcription factor activity, enhancer binding; transcription coactivator activity
Biological Process: muscle cell fate commitment; muscle development; myotube cell development; positive regulation of muscle cell differentiation; positive regulation of myoblast differentiation; positive regulation of skeletal muscle fiber development; positive regulation of transcription from RNA polymerase II promoter; protein amino acid phosphorylation; regulation of RNA splicing; regulation of transcription from RNA polymerase II promoter; skeletal muscle development
Product References and Citations for anti-MYOD1 antibody
Thulasi R et. al. Cell Growth and Differentiation, 1996, 7(4):531-41. Wesche WA et. al. American Journal of Surgical Pathology, 1995, 19(3):261-9. Parham DM et. al. Acta Neuropathologica, 1994, 87:605-11.
Research Articles on MYOD1
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Products associated with anti-MYOD1 antibody
Pathways associated with anti-MYOD1 antibody
Diseases associated with anti-MYOD1 antibody
Organs/Tissues associated with anti-MYOD1 antibody
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