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anti-ORC3L antibody :: Rat anti-Human ORC3L Monoclonal Antibody

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Catalog # MBS375198
Unit / Price
  0.05 mL  /  $370 +1 FREE 8GB USB
Testing Data
Product Name

ORC3L, Monoclonal Antibody

Popular Item
Also Known As

Rat Anti-ORC3L [1D6]

Product Synonym Names
Homolog of Latheo antibody; homolog of latheo, Drosophila antibody; LAT antibody; LATHEOantibody; LATHEO, drosophila, homolog of antibody; Orc3 antibody; Origin recognition complex subunit 3antibody; Origin Recognition Complex Subunit 3 Isoform 1 antibody; Origin recognition complex subunit Latheoantibody; Origin Recognition Complex, subunit 3, S. cerevisiae, homolog of antibody; Origin recognition complex,subunit 3-like (S. cerevisiae) antibody; Origin recognition complex, subunit 3-like (yeast)antibody
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
568
OMIM
604972
3D Structure
ModBase 3D Structure for Q9UBD5
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
1D6
Host
Rat
Species Reactivity
Human
Purity/Purification
Protein G
Form/Format
Purified antibody containing PBS 0.1% sodium azide
Concentration
0.1mg/ml (lot specific)
Target Antigen
ORC3L
Immunogen
Full length human ORC3L protein
Myeloma/fusion Partners
P3-x63Ag.8.653
Research Areas
DNA Synthesis
Other Notes
Small volumes of anti-ORC3L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ORC3L antibody
Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-ORC3L antibody
Optimal antibody dilution should be determined by titration, however as a guideline try; WB: Use at 1:1000. Predicted molecular weight: 82 kDa

Testing Data of anti-ORC3L antibody
anti-ORC3L antibody Testing Data image
NCBI/Uniprot data below describe general gene information for ORC3L. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
65,929 Da
NCBI Official Full Name
origin recognition complex subunit 3 isoform 3
NCBI Official Synonym Full Names
origin recognition complex, subunit 3
NCBI Official Symbol
NCBI Official Synonym Symbols
LAT; ORC3L; LATHEO
  [Similar Products]
NCBI Protein Information
origin recognition complex subunit 3; homolog of latheo, Drosophila; origin recognition complex subunit Latheo; origin recognition complex, subunit 3 honolog
UniProt Protein Name
Origin recognition complex subunit 3
UniProt Synonym Protein Names
Origin recognition complex subunit Latheo
UniProt Gene Name
UniProt Synonym Gene Names
LATHEO; ORC3L  [Similar Products]
UniProt Entry Name
ORC3_HUMAN
NCBI Summary for ORC3L
The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for ORC3L
ORC3L: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Belongs to the ORC3 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell cycle regulation

Chromosomal Location of Human Ortholog: 6q14.3-q16.1

Cellular Component: nucleoplasm; nuclear origin of replication recognition complex; origin recognition complex

Molecular Function: protein binding; DNA replication origin binding

Biological Process: mitotic cell cycle; DNA replication; G1/S transition of mitotic cell cycle
Product References and Citations for anti-ORC3L antibody
Human origin recognition complex binds to the region of the latent origin of DNA replication of EpsteinBarr virus. Schepers A et al. (Embo J,Aug 2001)PUBMED

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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