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anti-PLEK antibody :: Mouse anti-Human PLEK Monoclonal Antibody

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Catalog # MBS2541363
Unit / Price
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  0.06 mL  /  $220 +1 FREE 8GB USB
  0.12 mL  /  $290 +1 FREE 8GB USB
  0.2 mL  /  $435 +1 FREE 8GB USB
Western Blot (WB)
Product Name

PLEK, Monoclonal Antibody

Full Product Name

PLEK Monoclonal Antibody

Product Synonym Names
FLJ27168; OTTHUMP00000159962; p47; Platelet 47 kDa protein; Platelet and leukocyte C kinase substrate; Platelet P47; Platelet p47 protein; Pleckstrin; PLEK; PLEK
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
173570 geneneXtProt; the human protein knowledge platformMore
3D Structure
ModBase 3D Structure for P08567
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1D5C2
Host
Mouse
Species Reactivity
Human
Purity/Purification
Protein G purification
Concentration
1mg/mL (lot specific)
Immunogen
Fusion protein of PLEK
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-PLEK antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PLEK antibody
PLEK (pleckstrin; also known as p47) was originally identified as the major PKC substrate in platelets and later is found to be expressed in all cells of the hemopoietic system. Through two pleckstrin homology (PH) domains at its N and C termini, PLEK may interact with various protein and/or lipid ligands and serve as an intracellular adaptor/targeting protein. Predominantly cytosolic in unstimulated cells, PLEK would undergo transient redistribution to phagosomal membrane in response to stimuli. PLEK has been found to be hyperphosphorylated in diabetic mononuclear phagocytes and promote proinflammatory cytokine secretion in diabetes. (10477609, 17579087)
Applications Tested/Suitable for anti-PLEK antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-PLEK antibody
WB: 1:2000-1:20000
IHC: 1:50-1:500

Western Blot (WB) of anti-PLEK antibody
Western Blot analysis of HL-60 cells using PLEK Monoclonal Antibody at dilution of 1:5000
anti-PLEK antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for PLEK. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated: 40kDa
Observed: 40-47kDa
NCBI Official Full Name
pleckstrin
NCBI Official Synonym Full Names
pleckstrin
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
pleckstrin
UniProt Protein Name
Pleckstrin
UniProt Synonym Protein Names
Platelet 47 kDa protein; p47
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
P47; p47  [Similar Products]
UniProt Comments for PLEK
Major protein kinase C substrate of platelets.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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