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anti-PSA antibody :: anti-Human Prostate Specific Antigen Monoclonal Antibody

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Catalog # MBS312867
Unit / Price
  1 mg  /  $310 +1 FREE 8GB USB
Testing Data
Product Name

Prostate Specific Antigen (PSA), Monoclonal Antibody

Also Known As

MAb to PSA Free

Product Synonym Names
Prostate Specific Antigen (PSA) Free
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
261
Chromosome Location
Chromosome: 19; NC_000019.9 (51358171..51364020). Location: 19q13.41
OMIM
176820
3D Structure
ModBase 3D Structure for P07288
Clonality
Monoclonal
Isotype
IgG2b, kappa
Clone Number
B729M
Host
Host: Mouse
Source: Ascites
Species Reactivity
Human
Specificity
Prostate Specific Antigen (PSA) Free
Purity/Purification
>= 90% pure (SDS-PAGE). Protein A chromatography. Product is 0.2um filtered.
Form/Format
Purified, Liquid
Concentration
6.6mg/ml (OD280nm, E^0.1% = 1.4) (lot specific)
Immunogen
Purified PSA
Species Specificity
Reacts with free PSA.
Affinity Constant
Not determined
Buffer
PBS, pH 7.4 +/- 0.2
Preservative
NaN3 (0.05% Sodium azide)
Warning
This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Preparation and Storage
Upon receipt, aliquot and store at -40 degree C. Avoid multiple freeze/thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-PSA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-PSA antibody
MAb to PSA Free
Monoclonal Antibody to Human Prostate Specific Antigen (PSA) Free
Applications Tested/Suitable for anti-PSA antibody
ELISA
Application Notes for anti-PSA antibody
Suitable for use in indirect ELISA.

Testing Data of anti-PSA antibody
anti-PSA antibody Testing Data image
NCBI/Uniprot data below describe general gene information for PSA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28,741 Da
NCBI Official Full Name
prostate-specific antigen isoform 1 preproprotein
NCBI Official Synonym Full Names
kallikrein-related peptidase 3
NCBI Official Symbol
NCBI Official Synonym Symbols
APS; PSA; hK3; KLK2A1
  [Similar Products]
NCBI Protein Information
prostate-specific antigen; seminin; P-30 antigen; kallikrein-3; semenogelase; gamma-seminoprotein; prostate specific antigen
UniProt Protein Name
Prostate-specific antigen
UniProt Synonym Protein Names
Gamma-seminoprotein; Seminin; Kallikrein-3; P-30 antigen; Semenogelase
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
KLK3_HUMAN
NCBI Summary for PSA
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq]
UniProt Comments for PSA
Function: Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Catalytic activity: Preferential cleavage: -Tyr-|-Xaa-.

Enzyme regulation: Activity is strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. Ref.18

Subcellular location: Secreted.

Sequence similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.Contains 1 peptidase S1 domain.

Sequence caution: The sequence AAD14185.1 differs from that shown. Reason: Erroneous initiation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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