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anti-RARG antibody :: Mouse anti-Human RARG Monoclonal Antibody

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Catalog # MBS120110
Unit / Price
  0.1 mg  /  $345 +1 FREE 8GB USB
Quality Control
Product Name

RARG, Monoclonal Antibody

Full Product Name

Mouse monoclonal antibody Anti-Human RARG

Product Synonym Names
Homo sapiens retinoic acid receptor, gamma (RARG), mRNA; RARC; NR1B3
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clone Number
Species Reactivity
100 ug/ml (1.0 ml) (lot specific)
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Filtered through a 0.22 um membrane.
Other Notes
Small volumes of anti-RARG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RARG antibody
This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression.
Applications Tested/Suitable for anti-RARG antibody
Dot Blot (DB)

Quality Control of anti-RARG antibody
Left: Western blot analysis of immunized recombinant protein, using anti-RARG monoclonal antibody.
anti-RARG antibody Quality Control image
NCBI/Uniprot data below describe general gene information for RARG. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47,931 Da
NCBI Official Full Name
Homo sapiens retinoic acid receptor, gamma (RARG), transcript variant 1, mRNA
NCBI Official Synonym Full Names
retinoic acid receptor, gamma
NCBI Official Symbol
NCBI Official Synonym Symbols
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NCBI Protein Information
retinoic acid receptor gamma; RAR-gamma; nuclear receptor subfamily 1 group B member 3; retinoic acid nuclear receptor gamma variant 1; retinoic acid nuclear receptor gamma variant 2
UniProt Protein Name
Retinoic acid receptor gamma
UniProt Synonym Protein Names
Nuclear receptor subfamily 1 group B member 3
Protein Family
UniProt Gene Name
UniProt Entry Name
NCBI Summary for RARG
This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
UniProt Comments for RARG
RARG: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function. Homodimer. Heterodimer with a RXR molecule. Binds DNA preferentially as a RAR/RXR heterodimer. Forms a complex with PUS1 and the SRA1 RNA in the nucleus. Belongs to the nuclear hormone receptor family. NR1 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding; Nuclear receptor

Chromosomal Location of Human Ortholog: 12q13

Cellular Component: nucleoplasm; transcription factor complex; nuclear chromatin; integral to membrane; nucleus

Molecular Function: retinoid X receptor binding; protein binding; DNA binding; zinc ion binding; steroid hormone receptor activity; retinoic acid receptor activity; transcription factor activity

Biological Process: retinoic acid receptor signaling pathway; transcription initiation from RNA polymerase II promoter; response to retinoic acid; regulation of myelination; glandular epithelial cell development; embryonic eye morphogenesis; positive regulation of apoptosis; multicellular organism growth; negative regulation of chondrocyte differentiation; negative regulation of transcription from RNA polymerase II promoter; Wnt receptor signaling pathway through beta-catenin; embryonic hindlimb morphogenesis; embryonic camera-type eye development; anterior/posterior pattern formation; negative regulation of cell proliferation; positive regulation of programmed cell death; neural tube closure; positive regulation of cell proliferation; gene expression; steroid hormone mediated signaling; positive regulation of transcription from RNA polymerase II promoter; transmembrane transport; regulation of cell size; negative regulation of apoptosis
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