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anti-RBP4 antibody :: anti-Human Retinol Binding Protein 4 (RBP4) Monoclonal Antibody

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Catalog # MBS312623
Unit / Price
  1 mg  /  $830 +1 FREE 8GB USB
anti-RBP4 antibody
Product Name

Retinol Binding Protein 4 (RBP4), Monoclonal Antibody

Also Known As

MAb to Retinol Binding Prot. 4

Product Synonym Names
Monoclonal Antibody to Human Retinol Binding Protein 4 (RBP4)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 10; NC_000010.10 (95351593..95360993, complement). Location: 10q23-q24
OMIM
180250
3D Structure
ModBase 3D Structure for P02753
Clonality
Monoclonal
Isotype
IgG1
Clone Number
B578M
Host
Host: Mouse. Hybridization of Sp 2/0 myeloma cells with spleen cells from BALB/c mice.
Source: Ascites
Species Reactivity
Human
Specificity
Retinol Binding Protein 4 (RBP4)
Human plasma RBP4. Recognizes free RBP4 and RBP4 in complex with transthyretin. Reacts with apo-RBP4 and holo-RBP4.
Purity/Purification
>90% pure (SDS-PAGE). Protein A chromatography
Form/Format
Purified, Liquid
Immunogen
Human recombinant RBP4
Affinity Constant
Not determined
Buffer
PBS, pH 7.4
Preservative
0.1% Sodium azide
Notes
Some applications in which these products may be used are covered by patents issued and applicable in certain countries. Because purchase of these products does not include a license to perform any patented application, users of these products may
Important Note
Centrifuge before opening to ensure complete recovery of vial contents.
Warnings
This product contains sodium azide, which has been classified as Xn (Harmful), in European Directive 67/548/EEC in the concentration range of 0.1 - 1.0 %. When disposing of this reagent through lead or copper plumbing, flush with copious volumes of water to prevent azide build-up in drains.
Preparation and Storage
Store at 2 to 8 degree C.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-RBP4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-RBP4 antibody
EIA/ELISA, Western Blot, Immunoassay Antibody Pairs
NCBI/Uniprot data below describe general gene information for RBP4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,010 Da[Similar Products]
NCBI Official Full Name
Retinol-binding protein 4
NCBI Official Synonym Full Names
retinol binding protein 4, plasma
NCBI Official Symbol
NCBI Protein Information
retinol-binding protein 4; RBP; PRBP; OTTHUMP00000020114; OTTHUMP00000020115; OTTHUMP00000020116; plasma retinol-binding protein; retinol-binding protein 4, interstitial
UniProt Protein Name
Retinol-binding protein 4
UniProt Synonym Protein Names
Plasma retinol-binding protein
Protein Family
UniProt Gene Name
UniProt Entry Name
RET4_HUMAN
NCBI Summary for RBP4
This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells. [provided by RefSeq]
UniProt Comments for RBP4
Function: Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.

Subcellular location: Secreted.

Involvement in disease: Defects in RBP4 are a cause of retinol-binding protein deficiency (RBP deficiency) [

MIM:180250]. This condition causes night vision problems. It produces a typical 'fundus xerophthalmicus', featuring a progressed atrophy of the retinal pigment epithelium.

Sequence similarities: Belongs to the calycin superfamily. Lipocalin family.

Mass spectrometry: Molecular mass is 21063.46±1.88 Da from positions 17 - 199. Determined by ESI. Ref.10Molecular mass is 20534 Da from positions 19 - 197. Determined by MALDI. Ref.12Molecular mass is 20162 Da from positions 19 - 194. Determined by MALDI. Ref.12

Sequence caution: The sequence AAF69622.1 differs from that shown. Reason: Erroneous initiation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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