• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-SNCG antibody :: Mouse anti-Human SNCG Monoclonal Antibody

Scan QR to view Datasheet
Catalog # MBS9602384
Unit / Price
  0.05 mL  /  $235 +1 FREE 8GB USB
  0.1 mL  /  $295 +1 FREE 8GB USB
  0.2 mL  /  $370 +1 FREE 8GB USB
Western Blot (WB)
Product Name

SNCG, Monoclonal Antibody

Popular Item
Also Known As

SNCG (breast cancer-specific protein 1) Antibody

Product Synonym Names
BCSG1; Breast cancer specific gene 1 protein; Breast cancer specific protein 1; Breast cancer-specific gene 1 protein; Gamma synuclein; Gamma-synuclein; Persyn; PRSN; SNCG; SR; Synoretin; Synuclein gamma; synuclein, gamma (breast cancer-specific protein 1); SYUG_HUMAN
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
126
3D Structure
ModBase 3D Structure for O76070
Clonality
Monoclonal
Isotype
IgG1
Host
Mouse
Species Reactivity
Human
Specificity
SNCG (breast cancer-specific protein 1) antibody detects endogenous levels of total SNCG (breast cancer-specific protein 1)
Purity/Purification
Affinity-Chromatography
Form/Format
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (lot specific)
Immunogen
Purified recombinant fragment of human SNCG (breast cancer-specific protein 1) expressed in E. Coli
Subcellular Location
Cytoplasm > Perinuclear Region. Cytoplasm > Cytoskeleton > Centrosome. Cytoplasm > Cytoskeleton > Spindle. Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
Tissue Specificity
Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-SNCG antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SNCG antibody
Description: SNCG(also designated gamma-synuclein or breast cancer-specific protein 1), with 127-amino acid protein(about 14kDa), belongs to the synuclein family, which also includes alpha-and beta-synuclein.Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals, while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, including liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.
Function: Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway (By similarity).
Subunit Structure: May be a centrosome-associated protein. Interacts with MYOC; affects its secretion and its aggregation (By similarity).
Post-translational Modifications: Phosphorylated. Phosphorylation by GRK5 appears to occur on residues distinct from the residue phosphorylated by other kinases.
Similarity: Belongs to the synuclein family.
Applications Tested/Suitable for anti-SNCG antibody
Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
Application Notes for anti-SNCG antibody
ELISA: 1:10000
WB: 1:500-1:2000
IHC: 1:200-1:1000
IF/ICC: 1:100-1:500

Western Blot (WB) of anti-SNCG antibody
Figure 1: Western blot analysis using SNCG mouse mAb against truncated SNCG recombinant protein.
anti-SNCG antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for SNCG. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Observed: 13 kDa
Predicted: 14 kDa
NCBI Official Full Name
gamma-synuclein isoform 2
NCBI Official Synonym Full Names
synuclein gamma
NCBI Official Symbol
NCBI Official Synonym Symbols
SR; BCSG1
  [Similar Products]
NCBI Protein Information
gamma-synuclein
UniProt Protein Name
Gamma-synuclein
UniProt Synonym Protein Names
Breast cancer-specific gene 1 protein; Persyn; Synoretin; SR
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
BCSG1; PERSYN; PRSN; SR  [Similar Products]
NCBI Summary for SNCG
This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development. [provided by RefSeq, Jan 2010]
UniProt Comments for SNCG
Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000