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anti-SRD5A1 antibody :: Mouse anti-Human SRD5A1 Monoclonal Antibody

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Catalog # MBS2549145
Unit / Price
  0.06 mL  /  $220 +1 FREE 8GB USB
  0.12 mL  /  $290 +1 FREE 8GB USB
  0.2 mL  /  $435 +1 FREE 8GB USB
Western Blot (WB)
Product Name

SRD5A1, Monoclonal Antibody

Also Known As

SRD5A1 Monoclonal Antibody

Product Synonym Names
S5AR 1; SR type 1; SRD5A1; Steroid 5 alpha reductase 1
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
1312
OMIM
M32313 mRNA
3D Structure
ModBase 3D Structure for P18405
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1D5D8
Host
Mouse
Species Reactivity
Human
Purity/Purification
Protein G Purification
Concentration
1mg/mL (lot specific)
Immunogen
Fusion Protein of SRD5A1
Buffer
PBS with 0.02% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of anti-SRD5A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SRD5A1 antibody
Steroid 5-alpha-reductase (SRD5A1) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). SRD5A1 is a minor component of the reductase activity in prostate although the gene was originally cloned from prostate. On the other hand,  SRD5A1 appears to be the predominant isozyme of steroid 5-alpha-reductase in the scalp and elsewhere in the skin.
Applications Tested/Suitable for anti-SRD5A1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-SRD5A1 antibody
WB: 1:500-1:5000
IHC: 1:50-1:500
IF: 1:50-1:500

Western Blot (WB) of anti-SRD5A1 antibody
Western Blot analysis of Human testis tissue using SRD5A1 Monoclonal Antibody at dilution of 1:1000
anti-SRD5A1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for SRD5A1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32kDa
NCBI Official Full Name
Homo sapiens steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1), mRNA
NCBI Official Synonym Full Names
steroid 5 alpha-reductase 1
NCBI Official Symbol
SRD5A1  [Similar Products]
NCBI Official Synonym Symbols
S5AR 1
  [Similar Products]
NCBI Protein Information
3-oxo-5-alpha-steroid 4-dehydrogenase 1
UniProt Protein Name
3-oxo-5-alpha-steroid 4-dehydrogenase 1
UniProt Synonym Protein Names
SR type 1; Steroid 5-alpha-reductase 1; S5AR 1
UniProt Gene Name
SRD5A1  [Similar Products]
UniProt Synonym Gene Names
S5AR 1  [Similar Products]
NCBI Summary for SRD5A1
Steroid 5-alpha-reductase (EC 1.3.99.5) catalyzes the conversion of testosterone into the more potent androgen, dihydrotestosterone (DHT). Also see SRD5A2 (MIM 607306).[supplied by OMIM, Mar 2008]
UniProt Comments for SRD5A1
SRD5A1: Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. Belongs to the steroid 5-alpha reductase family.

Protein type: EC 1.3.1.22; Lipid Metabolism - androgen and estrogen; Membrane protein, integral; Membrane protein, multi-pass; Oxidoreductase

Chromosomal Location of Human Ortholog: 5p15.31

Cellular Component: cell soma; endoplasmic reticulum membrane; integral component of membrane; myelin sheath; perinuclear region of cytoplasm

Molecular Function: 3-oxo-5-alpha-steroid 4-dehydrogenase activity; amide binding; cholestenone 5-alpha-reductase activity; electron transfer activity

Biological Process: androgen biosynthetic process; cell differentiation; cellular response to insulin stimulus; cellular response to starvation; cerebral cortex development; circadian sleep/wake cycle, REM sleep; diterpenoid metabolic process; female genitalia development; hippocampus development; hypothalamus development; liver development; male genitalia development; male gonad development; pituitary gland development; progesterone metabolic process; response to drug; response to estrogen; response to follicle-stimulating hormone stimulus; response to muscle activity; serotonin metabolic process; sex determination; spinal cord development; thalamus development; urogenital system development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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