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anti-UBE2A antibody :: Mouse anti-Human UBE2A Monoclonal Antibody

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Catalog # MBS120202
Unit / Price
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  0.1 mg  /  $395 +1 FREE 8GB USB
Product Name

UBE2A, Monoclonal Antibody

Full Product Name

Mouse monoclonal antibody Anti-Human UBE2A

Product Synonym Names
Homo sapiens ubiquitin-conjugating enzyme E2A (RAD6 homolog)(UBE2A) gene
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
300860
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
2782C5
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Other Notes
Small volumes of anti-UBE2A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-UBE2A antibody
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Multiple alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. [NCBI Entrez Gene Summary]
Applications Tested/Suitable for anti-UBE2A antibody
Dot Blot (DB)

Quality Control of anti-UBE2A antibody
Western blot analysis of immunized recombinant protein, using anti-UBE2A monoclonal antibody.
anti-UBE2A antibody Quality Control image
Quality Control #2 of anti-UBE2A antibody
Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.
anti-UBE2A antibody Quality Control #2 image
NCBI/Uniprot data below describe general gene information for UBE2A. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Secondary Accession #
Molecular Weight
8,833 Da
NCBI Official Full Name
Homo sapiens ubiquitin-conjugating enzyme E2A (RAD6 homolog) (UBE2A) gene, complete cds
UniProt Protein Name
Ubiquitin-conjugating enzyme E2 A
UniProt Synonym Protein Names
RAD6 homolog A; HR6A; hHR6A; Ubiquitin carrier protein A; Ubiquitin-protein ligase A
UniProt Gene Name
UBE2A  [Similar Products]
UniProt Entry Name
UBE2A_HUMAN
UniProt Comments for UBE2A
UBE2A: a ubiquitin-protein ligase, a member of the ubiquitin-conjugating enzyme family. Homologous to the yeast DNA repair gene RAD6. Interacts with RAD18. Required for postreplication repair of UV-damaged DNA.

Protein type: Ligase; Ubiquitin ligase; EC 6.3.2.19; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: Xq24

Cellular Component: XY body; nuclear chromatin; cytoplasm; chromatin; cytosol

Molecular Function: protein binding; small conjugating protein ligase activity; ubiquitin protein ligase binding; ubiquitin-protein ligase activity; ATP binding; ligase activity

Biological Process: ubiquitin-dependent protein catabolic process; proteasomal ubiquitin-dependent protein catabolic process; antigen processing and presentation of peptide antigen via MHC class I; protein autoubiquitination; maternal process involved in pregnancy; protein polyubiquitination; postreplication repair; in utero embryonic development; positive regulation of cell proliferation; DNA repair; histone H2A ubiquitination; response to UV

Disease: Mental Retardation, X-linked, Syndromic, Nascimento Type
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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