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anti-YEATS4 antibody :: Mouse anti-Human YEATS4 Monoclonal Antibody

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Catalog # MBS120135
Unit / Price
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  0.1 mg  /  $395 +1 FREE 8GB USB
Quality Control
Product Name

YEATS4, Monoclonal Antibody

Full Product Name

Mouse monoclonal antibody Anti-Human YEATS4

Product Synonym Names
Homo sapiens YEATS domain containing 4 (YEATS4); YAF9; GAS41;NUBI-1; 4930573H17Rik; B230215M10Rik
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
602116
Clonality
Monoclonal
Isotype
IgG1
Clone Number
YEATB1A8
Host
Mouse
Species Reactivity
Human
Concentration
100 ug/ml (1.0 ml) (lot specific)
Preparation
This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Sterility
Filtered through a 0.22 um membrane.
Other Notes
Small volumes of anti-YEATS4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-YEATS4 antibody
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. [NCBI Entrez Gene Summary]
Applications Tested/Suitable for anti-YEATS4 antibody
Dot Blot (DB)

Quality Control of anti-YEATS4 antibody
Left: Western blot analysis of immunized recombinant protein, using anti-YEATS4 monoclonal antibody.
anti-YEATS4 antibody Quality Control image
NCBI/Uniprot data below describe general gene information for YEATS4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26,499 Da
NCBI Official Full Name
Homo sapiens YEATS domain containing 4 (YEATS4), transcript variant 1, mRNA
NCBI Official Synonym Full Names
YEATS domain containing 4
NCBI Official Symbol
YEATS4  [Similar Products]
NCBI Official Synonym Symbols
YAF9; GAS41; NUBI-1; 4930573H17Rik; B230215M10Rik
  [Similar Products]
NCBI Protein Information
YEATS domain-containing protein 4; NuMA binding protein 1; glioma-amplified sequence 41; glioma-amplified sequence-41; nuBI1; nuMA-binding protein 1
UniProt Protein Name
YEATS domain-containing protein 4
UniProt Synonym Protein Names
Glioma-amplified sequence 41; Gas41; NuMA-binding protein 1; NuBI-1; NuBI1
UniProt Gene Name
YEATS4  [Similar Products]
UniProt Entry Name
YETS4_HUMAN
NCBI Summary for YEATS4
The protein encoded by this gene is found in the nucleoli. It has high sequence homology to human MLLT1, and yeast and human MLLT3 proteins. Both MLLT1 and MLLT3 proteins belong to a class of transcription factors, indicating that the encoded protein might also represent a transcription factor. This protein is thought to be required for RNA transcription. This gene has been shown to be amplified in tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
UniProt Comments for YEATS4
YEATS4: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 12q13-q15

Cellular Component: nucleoplasm; NuA4 histone acetyltransferase complex; nuclear matrix; cytoplasm; nucleolus

Molecular Function: protein C-terminus binding; protein binding; DNA binding; structural constituent of cytoskeleton; transcription factor activity

Biological Process: mitosis; establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; regulation of growth; positive regulation of transcription, DNA-dependent
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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