• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-ARHGDIA antibody :: Mouse ARHGDIA Monoclonal Antibody

Scan QR to view Datasheet
Catalog # MBS9382981
Unit / Price
  0.05 mL  /  $270 +1 FREE 8GB USB
  0.1 mL  /  $445 +1 FREE 8GB USB
Western Blot (WB)
Product Name

ARHGDIA, Monoclonal Antibody

Popular Item
Also Known As

ARHGDIA Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
204
OMIM
X69550 mRNA
3D Structure
ModBase 3D Structure for P52565
Clonality
Monoclonal
Host
Mouse
Species Reactivity
Human, Mouse, Monkey
Specificity
ARHGDIA antibody detects endogeneous levels of total ARGHDIA
Purity/Purification
Affinity-chromatography
Form/Format
Mouse IgG1 in phosphate buffered saline ( without Mg2 and Ca 2, pH 7.4, 150 mM NaCI, 0.02% Sodium azide and 50% Glycerol.
Immunogen
Purified recombinant fragment of human ARHGDIA expressed in E.Coli
Subcellular Location
Cytoskeleton, Cytosol; Extracellular region or secreted.
Similarity
Belongs to the Rho GDI family.
Preparation and Storage
Store at -20°C. Stable for 12 months from date of receipt.
Other Notes
Small volumes of anti-ARHGDIA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ARHGDIA antibody
Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
Applications Tested/Suitable for anti-ARHGDIA antibody
ELISA, WB, ICC, FCM
Application Notes for anti-ARHGDIA antibody
ELISA 1/10000
WB 1/500-1/2000
ICC 1/200-1/1000
FCM 1/200-1/400

Western Blot (WB) of anti-ARHGDIA antibody
Western Blot analysis using ARHGDIA mAb against human ARHGDIA recombinant protein.(Expected MW is 48.7 kDa)
anti-ARHGDIA antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for ARHGDIA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26 kDa
NCBI Official Full Name
rho GDP-dissociation inhibitor 1 isoform a
NCBI Official Synonym Full Names
Rho GDP dissociation inhibitor alpha
NCBI Official Symbol
ARHGDIA  [Similar Products]
NCBI Official Synonym Symbols
GDIA1; NPHS8; RHOGDI; RHOGDI-1; HEL-S-47e
  [Similar Products]
NCBI Protein Information
rho GDP-dissociation inhibitor 1
UniProt Protein Name
Rho GDP-dissociation inhibitor 1
UniProt Synonym Protein Names
Rho-GDI alpha
UniProt Gene Name
ARHGDIA  [Similar Products]
UniProt Synonym Gene Names
GDIA1; Rho GDI 1  [Similar Products]
NCBI Summary for ARHGDIA
This gene encodes a protein that plays a key role in the regulation of signaling through Rho GTPases. The encoded protein inhibits the disassociation of Rho family members from GDP (guanine diphosphate), thereby maintaining these factors in an inactive state. Activity of this protein is important in a variety of cellular processes, and expression of this gene may be altered in tumors. Mutations in this gene have been found in individuals with nephrotic syndrome, type 8. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
UniProt Comments for ARHGDIA
RhoGDI alpha: Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Monomer. Forms a heterodimer with RAC1. Interacts with FER. Belongs to the Rho GDI family.

Protein type: Apoptosis; Cell adhesion; Cell development/differentiation; G protein regulator, misc.; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17q25.3

Cellular Component: cytoskeleton; cytosol

Molecular Function: protein binding

Biological Process: cell motility; negative regulation of apoptosis; negative regulation of axonogenesis; negative regulation of cell adhesion; positive regulation of axonogenesis; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction

Disease: Nephrotic Syndrome, Type 8
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000