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anti-CD37 antibody :: Mouse anti-Human, Mouse CD37 Monoclonal Antibody

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Catalog # MBS246100
Unit / Price
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  0.05 mL  /  $530 +1 FREE 8GB USB
Product Name

CD37, Monoclonal Antibody

Full Product Name

Mouse Monoclonal [clone 2B8] (IgG1) to Human CD37

Product Synonym Names
Anti-CD37 Antibody (clone 2B8) IHC-plus; CD37; CD37 antigen; CD37 molecule; Leukocyte surface antigen CD37; gp52-40; TSPAN26; Leukocyte antigen CD37; Tetraspanin-26; Tspan-26; Human CD37
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
151523
3D Structure
ModBase 3D Structure for P11049
Clonality
Monoclonal
Isotype
IgG1
Clone Number
2B8
Host
Mouse
Species Reactivity
Human, Mouse
Specificity
Human CD37
Purity/Purification
Ascites
Form/Format
Ascites fluid, 0.03% sodium azide. Sourced in Ascites.
Target Species
Human
Immunogen Description
Purified recombinant fragment of CD37 expressed in E Coli.
Immunogen Type
Recombinant protein
Immunogen
CD37 antibody was raised against purified recombinant fragment of CD37 expressed in E Coli.
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of anti-CD37 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-CD37 antibody
Applications Tested/Suitable for anti-CD37 antibody
Immunohistochemistry (IHC - Paraffin), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-CD37 antibody
ELISA (1:10000), IF (1:200 - 1:1000), IHC-P (1:200 - 1:400)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti...

Immunohistochemistry (IHC) of anti-CD37 antibody
Anti-CD37 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
anti-CD37 antibody Immunohistochemistry (IHC) (IHC) image
Immunohistochemistry (IHC) of anti-CD37 antibody
Anti-CD37 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
anti-CD37 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for CD37. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
22,563 Da
NCBI Official Full Name
leukocyte antigen CD37 isoform A
NCBI Official Synonym Full Names
CD37 molecule
NCBI Official Symbol
NCBI Official Synonym Symbols
GP52-40; TSPAN26
  [Similar Products]
NCBI Protein Information
leukocyte antigen CD37; tspan-26; tetraspanin-26; leukocyte surface antigen CD37; cell differentiation antigen 37
UniProt Protein Name
Leukocyte antigen CD37
UniProt Synonym Protein Names
Tetraspanin-26; Tspan-26; CD_antigen: CD37
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
TSPAN26; Tspan-26  [Similar Products]
UniProt Entry Name
CD37_HUMAN
NCBI Summary for CD37
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
UniProt Comments for CD37
CD37: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: membrane; integral to membrane; immunological synapse

Molecular Function: protein binding

Biological Process: negative regulation of cell proliferation; positive regulation of immunoglobulin production; negative regulation of myeloid dendritic cell activation; regulation of humoral immune response; regulation of defense response to virus; defense response to protozoan
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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