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anti-CKMT1 antibody :: Mouse anti-Human, Mouse CKMT1 Monoclonal Antibody

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Catalog # MBS475046
Unit / Price
  0.1 mL  /  $335 +1 FREE 8GB USB
Western Blot (WB)
Product Name

CKMT1, Monoclonal Antibody

Popular Item
Full Product Name

Anti-CKMT1 Mouse mAb

Product Synonym Names
Acidic type mitochondrial creatine kinase; CKMT; CKMT1; CKMT1A; CKMT1B; Creatine kinase mitochondrial 1 ubiquitous; Creatine kinase U type, mitochondrial; Creatine kinase ubiquitous mitochondrial; Creatine kinase, mitochondrial 1 (ubiquitous); Creatine kinase, mitochondrial 1A; Creatine kinase, mitochondrial 1B; Mia CK; U MtCK; Ubiquitous mitochondrial creatine kinase; UMTCK
Product Synonym Gene Name
ckmt1b; CKMT; CKMT1; UMTCK; CKMT1A[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
J04469 Genomic DNA
3D Structure
ModBase 3D Structure for P12532
Clonality
Monoclonal
Isotype
IgG1
Clone Number
1A6-C7-G10
Host
Mouse
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purified
Form/Format
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%, glycerol
Concentration
1mg/ml (lot specific)
Conjugation
Unconjugated
Modification
Unmodification
Immunogen
Purified recombinant human CKMT1 protein fragments expressed in E Coli.
Sensitivity
This antibody detects endogenous levels of CKMT1 and does not cross-react with related proteins.
Sequence Similarities
Belongs to the ATP:guanido phosphotransferase family. Contains 1 phosphagen kinase C-terminal domain. Contains 1 phosphagen kinase N-terminal domain.
Subunit Structure
Exists as an octamer composed of four MTCK homodimers.
Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side.
Other Notes
Small volumes of anti-CKMT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CKMT1 antibody
Entrez Summary: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.
Applications Tested/Suitable for anti-CKMT1 antibody
Western Blot (WB)
Application Notes for anti-CKMT1 antibody
WB: 1:1000

Western Blot (WB) of anti-CKMT1 antibody
Western blot detection of CKMT1 in Mouse Colon, 293 and A431 cell lysates using CKMT1 mouse mAb (1:1000 diluted).Predicted band size:47KDa.Observed band size:47KDa.
anti-CKMT1 antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for CKMT1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
47 kDa
NCBI Official Full Name
creatine kinase U-type, mitochondrial isoform 1
NCBI Official Synonym Full Names
creatine kinase, mitochondrial 1A
NCBI Official Symbol
CKMT1A  [Similar Products]
NCBI Official Synonym Symbols
CKMT1; U-MtCK; mia-CK
  [Similar Products]
NCBI Protein Information
creatine kinase U-type, mitochondrial
UniProt Protein Name
Creatine kinase U-type, mitochondrial
UniProt Synonym Protein Names
Acidic-type mitochondrial creatine kinase; Mia-CK; Ubiquitous mitochondrial creatine kinase; U-MtCK
Protein Family
UniProt Gene Name
CKMT1A  [Similar Products]
UniProt Synonym Gene Names
CKMT; Mia-CK; U-MtCK  [Similar Products]
NCBI Summary for CKMT1
Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
UniProt Comments for CKMT1
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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