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anti-EAPP antibody :: Mouse anti-Human, Mouse EAPP Monoclonal Antibody

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Catalog # MBS375185
Unit / Price
  0.1 mL  /  $415 +1 FREE 8GB USB
Western Blot (WB)
Product Name

EAPP, Monoclonal Antibody

Also Known As

Mouse Anti-EAPP [1E4]

Product Synonym Names
E2F- associated phosphoprotein antibody; E2F 1 antibody; E2F transcription factor 1 antibody; E2F-1 antibody; E2F1 antibody; E2f1 E2F transcription factor 1 antibody; E2F1_HUMAN antibody; KIAA4009 antibody; mKIAA4009 antibody;
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
285
OMIM
609486
3D Structure
ModBase 3D Structure for Q56P03
Clonality
Monoclonal
Isotype
Ig
Clone Number
10000
Host
Mouse
Species Reactivity
Human, Mouse
Purity/Purification
Protein G
Form/Format
Purified antibody (from supernatant) containing PBS + 0.1% sodium azide
Concentration
1mg/ml (lot specific)
Target Antigen
EAPP
Immunogen
GST-N-terminal fragment of human EAPP
Myeloma/fusion Partners
X63-Ag8.653
Other Notes
Small volumes of anti-EAPP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-EAPP antibody
Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluoresence (IF)
Application Notes for anti-EAPP antibody
Optimal antibody dilution should be determined by titration, however as a guideline try up to 1:200 for western blot

Western Blot (WB) of anti-EAPP antibody
anti-EAPP antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for EAPP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
32,762 Da
NCBI Official Full Name
E2F-associated phosphoprotein
NCBI Official Synonym Full Names
E2F-associated phosphoprotein
NCBI Official Symbol
NCBI Official Synonym Symbols
BM036; C14orf11
  [Similar Products]
NCBI Protein Information
E2F-associated phosphoprotein
UniProt Protein Name
E2F-associated phosphoprotein
UniProt Gene Name
UniProt Synonym Gene Names
C14orf11; EAPP  [Similar Products]
UniProt Entry Name
EAPP_HUMAN
NCBI Summary for EAPP
This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation. [provided by RefSeq, Jul 2008]
UniProt Comments for EAPP
EAPP: May play an important role in the fine-tuning of both major E2F1 activities, the regulation of the cell-cycle and the induction of apoptosis. Promotes S-phase entry, and inhibits p14(ARP) expression. Interacts with E2F1. The C-terminal half binds the N- terminal of E2F1. Also interacts with E2F2 and E2F3, but not E2F4. Ubiquitously expressed. Highest levels in heart, placenta, skeletal muscle and pancreas. Lower levels in brain, lung and kidney. In the brain, expressed in all regions with high levels in the cerebellum and cerebral cortex. Expressed in COS1 and transformed skin fibroblasts.

Chromosomal Location of Human Ortholog: 14q13.1

Cellular Component: nucleoplasm; Golgi apparatus; cytoplasm; nucleus

Biological Process: positive regulation of RNA elongation from RNA polymerase II promoter; positive regulation of cell proliferation
Product References and Citations for anti-EAPP antibody
Novy et al, MBC Vol. 16, Issue 5, 2182-2190 PUBMED

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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