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anti-IL25 antibody :: Mouse anti-Human, Mouse IL25 / IL17E Monoclonal Antibody

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Catalog # MBS245013
Unit / Price
  0.05 mg  /  $530 +1 FREE 8GB USB
Immunohistochemistry (IHC)
Product Name

IL25 / IL17E, Monoclonal Antibody

Popular Item
Also Known As

Mouse Monoclonal [clone 68C1039.2] (IgG1) to Human IL25 / IL17E

Product Synonym Names
Anti-IL25 / IL17E Antibody (aa115-132, clone 68C1039.2) IHC-plus; IL25; Interleukin 17E; Interleukin 25; Interleukin-25; IL17E; IL-17E; IL-25; Interleukin-17E; Human IL25; IL17E
Product Synonym Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
177
OMIM
605658
3D Structure
ModBase 3D Structure for Q9H293
Clonality
Monoclonal
Isotype
IgG1
Clone Number
68C1039.2
Host
Mouse
Species Reactivity
Human, Mouse
Specificity
A synthetic peptide of amino acids 115-132, obtained from the human IL-17E protein sequence, was used as immunogen
Purity/Purification
Protein G Purified
Form/Format
PBS containing 0.05% BSA and 0.05% sodium azide. Sourced in TCS.
Concentration
1 mg/ml (lot specific)
Target Species
Human
Immunogen Description
Synthetic peptide from human IL25 / IL-25.
Immunogen Type
Synthetic peptide
Immunogen
IL25 / IL17E antibody was raised against synthetic peptide from human IL25 / IL-25.
Antigen Modification
aa115-132
Preparation and Storage
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of anti-IL25 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-IL25 antibody
The IL17 proteins are a family of potent cytokines that act to induce proinflammatory responses. Studies have shown that IL17E binds strongly to IL17RB. Receptor binding of ligand has been shown to lead to the activation of nuclear factor kappa-B and production of IL8.
Product Categories/Family for anti-IL25 antibody
Applications Tested/Suitable for anti-IL25 antibody
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
Application Notes for anti-IL25 antibody
IHC-P (10 ug/ml), WB (2 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib...

Immunohistochemistry (IHC) of anti-IL25 antibody
Anti-IL-25 antibody IHC of human adrenal cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
anti-IL25 antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for IL25. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
18,523 Da
NCBI Official Full Name
interleukin-25 isoform 1
NCBI Official Synonym Full Names
interleukin 25
NCBI Official Symbol
NCBI Official Synonym Symbols
IL17E
  [Similar Products]
NCBI Protein Information
interleukin-25; interleukin-17E
UniProt Protein Name
Interleukin-25
UniProt Synonym Protein Names
Interleukin-17E; IL-17E
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
IL17E; IL-25; IL-17E  [Similar Products]
UniProt Entry Name
IL25_HUMAN
NCBI Summary for IL25
The protein encoded by this gene is a cytokine that shares sequence similarity with interleukin 17. This cytokine can induce NF-kappaB activation, and stimulate the production of interleukin 8. Both this cytokine and interleukin 17B are ligands for the cytokine receptor IL17BR. Studies of a similar gene in mice suggest that this cytokine may be a pro-inflammatory cytokine favoring the Th2-type immune response. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
UniProt Comments for IL25
IL25: Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses. Belongs to the IL-17 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: extracellular space

Molecular Function: cytokine activity; interleukin-17E receptor binding

Biological Process: response to fungus; inflammatory response to antigenic stimulus; response to nematode; eosinophil differentiation; positive regulation of transcription from RNA polymerase II promoter
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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