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anti-MGP antibody :: Mouse anti-Human, Mouse MGP Monoclonal Antibody

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Catalog # MBS2541327
Unit / Price
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  0.06 mL  /  $220 +1 FREE 8GB USB
  0.12 mL  /  $290 +1 FREE 8GB USB
  0.2 mL  /  $435 +1 FREE 8GB USB
Western Blot (WB)
Product Name

MGP, Monoclonal Antibody

Full Product Name

MGP Monoclonal Antibody

Product Synonym Names
Cell growth inhibiting gene 36 protein; Cell growth-inhibiting gene 36 protein; GAMMA-CARBOXYGLUTAMIC ACID PROTEIN; MATRIX; GIG36; Matrix Gla protein; MGLAP; MGP; MGP; NTI
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
3D Structure
ModBase 3D Structure for P08493
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
1A1C3
Host
Mouse
Species Reactivity
Human, Mouse
Purity/Purification
Caprylic acid/ammonium sulfate precipitation
Concentration
1mg/mL (lot specific)
Immunogen
Fusion protein of MGP
Buffer
PBS with 0.1% sodium azide, 50% glycerol, PH7.3
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-MGP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MGP antibody
Matrix Gla protein (MGP) is is a vitamin K-dependent, extracellular matrix protein. MGP plays a pivotal role in preventing soft tissue calcification and local mineralization of the vascular wall. Vitamin K deficiency leads to inactive uncarboxylated MGP (ucMGP), which accumulates at sites of arterial calcification. However MGP is synthesized in many tissues and is especially enriched in embryonic tissues and in cancer cells. Defects in MGP are the cause of Keutel syndrome (KS), which is an autosomal recessive disorder characterized by abnormal cartilage calcification, peripheral pulmonary stenosis neural hearing loss and midfacial hypoplasia.
Product Categories/Family for anti-MGP antibody
Applications Tested/Suitable for anti-MGP antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-MGP antibody
WB: 1:500-1:5000
IHC: 1:20-1:200

Western Blot (WB) of anti-MGP antibody
Western Blot analysis of Transfected HEK-293 cells using MGP Monoclonal Antibody at dilution of 1:1000
anti-MGP antibody Western Blot (WB) (WB) image
NCBI/Uniprot data below describe general gene information for MGP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
Calculated: 13kDa
Observed: 12kDa
NCBI Official Full Name
matrix Gla protein isoform 2 preproprotein
NCBI Official Synonym Full Names
matrix Gla protein
NCBI Official Symbol
NCBI Official Synonym Symbols
NTI; GIG36; MGLAP
  [Similar Products]
NCBI Protein Information
matrix Gla protein
UniProt Protein Name
Matrix Gla protein
UniProt Synonym Protein Names
Cell growth-inhibiting gene 36 protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
MGLAP; MGP  [Similar Products]
NCBI Summary for MGP
This gene encodes a member of the osteocalcin/matrix Gla family of proteins. The encoded vitamin K-dependent protein is secreted by chondrocytes and vascular smooth muscle cells, and functions as a physiological inhibitor of ectopic tissue calcification. Carboxylation status of the encoded protein is associated with calcification of the vasculature in human patients with cardiovascular disease and calcification of the synovial membranes in osteoarthritis patients. Mutations in this gene cause Keutel syndrome in human patients, which is characterized by abnormal cartilage calcification, peripheral pulmonary stenosis and facial hypoplasia. [provided by RefSeq, Sep 2016]
UniProt Comments for MGP
Associates with the organic matrix of bone and cartilage. Thought to act as an inhibitor of bone formation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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