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anti-RNH1 antibody :: Mouse anti-Human, Mouse RNH1 Monoclonal Antibody

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Catalog # MBS200161
Unit / Price
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  0.05 mL  /  $240 +1 FREE 8GB USB
  0.1 mL  /  $315 +1 FREE 8GB USB
Product Name

RNH1, Monoclonal Antibody

Full Product Name

RNH1 antibody

Product Synonym Names
ribonuclease/angiogenin inhibitor 1; ribonuclease/angiogenin inhibitor; RAI
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
M22414 mRNA
3D Structure
ModBase 3D Structure for P13489
IgG2a, k
Clone Number
Species Reactivity
Human, Mouse
By protein-G affinity chromatography
Liquid. In phosphate-buffered saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol.
1mg/ml (lot specific)
Antigen Species
Recombinant Ribonuclease inhibitor 1 (RNH1) (7-461aa) purified from E. coli
Clone Note
Anti-human RNH1 mAb, clone AT1H23, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human RNH1 protein.
Preparation and Storage
Can be stored at 4 degree C.
For long term storage, aliquot and store at -20 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of anti-RNH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RNH1 antibody
Ribonuclease inhibitor 1 (RNH1) the placental ribonuclease inhibitor, is an acid protein with a molecular weight of 50 kDa. RNH1 is a member of a family of proteinaceous cytoplasmic RNase inhibitors that are expressed in many tissues and bind to both intracellular and extracellular RNases in the cytosol. RNH1 is a role in abolishing the ribonucleolytic and angiogenic activities of angiogenin.
Product Categories/Family for anti-RNH1 antibody
Applications Tested/Suitable for anti-RNH1 antibody
ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-RNH1 antibody
WB: 1:1000 ~ 2000.
Recommended starting dilution is 1:1000.

Western Blot (WB) of anti-RNH1 antibody
The Cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human RNH1 antibody (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1. : Jurkat cell lysate Lane 2. : HepG2 cell lysate
anti-RNH1 antibody Western Blot (WB) (WB) image
Immunofluorescence (IF) of anti-RNH1 antibody
ICC/IF analysis of RNH1 in PC3 cells line, stained with DAPI (Blue) for nucleus staining and monoclonal anti-human RNH1 antibody (1:100) with goat anti-mouse IgG-Alexa fluor 488 conjugate (Green).
anti-RNH1 antibody Immunofluorescence (IF) image
NCBI/Uniprot data below describe general gene information for RNH1. It may not necessarily be applicable to this product.
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
49,973 Da
NCBI Official Full Name
ribonuclease inhibitor
NCBI Official Synonym Full Names
ribonuclease/angiogenin inhibitor 1
NCBI Official Symbol
NCBI Official Synonym Symbols
  [Similar Products]
NCBI Protein Information
ribonuclease inhibitor
UniProt Protein Name
Ribonuclease inhibitor
UniProt Synonym Protein Names
Placental ribonuclease inhibitor; Placental RNase inhibitor; Ribonuclease/angiogenin inhibitor 1; RAI
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
PRI; RNH; Placental RNase inhibitor; RAI  [Similar Products]
NCBI Summary for RNH1
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010]
UniProt Comments for RNH1
Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis.
Product References and Citations for anti-RNH1 antibody
Park J.H., et al., (2008) Cytotechnology 57 (1):93-99 ; Johnson R.J., et al., (2007) J Mol Biol 368 (2):434-449; Fu P, et al., (2005) Cancer Gene Ther 12 (3):268-275

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