NP_001317428.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
28087 Da
NCBI Official Full Name
WW domain-binding protein 2 isoform 2
NCBI Official Synonym Full Names
WW domain binding protein 2
NCBI Protein Information
WW domain-binding protein 2
UniProt Protein Name
WW domain-binding protein 2
UniProt Synonym Gene Names
NCBI Summary for WBP2
The globular WW domain is composed of 38 to 40 semiconserved amino acids shared by proteins of diverse functions including structural, regulatory, and signaling proteins. The domain is involved in mediating protein-protein interactions through the binding of polyproline ligands. This gene encodes a WW domain binding protein that is a transcriptional coactivator of estrogen receptor alpha and progesterone receptor. Defects in this gene have been associated with hearing impairment. [provided by RefSeq, Jan 2017]
UniProt Comments for WBP2
WBP2: Binds to the WW domain of YAP1, WWP1 and WWP2. Interacts with NEDD4.
Protein type: Cell development/differentiation; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 17q25.1
Cellular Component: nuclear chromatin
Molecular Function: chromatin DNA binding; protein binding
Biological Process: establishment of protein localization; positive regulation of gene expression, epigenetic; positive regulation of transcription from RNA polymerase II promoter
Product References and Citations for anti-WBP2 antibody
Chen H.I.,et al.J. Biol. Chem. 272:17070-17077 (1997). Pirozzi G.,et al.J. Biol. Chem. 272:14611-14616 (1997). Burkard T.R.,et al.BMC Syst. Biol. 5:17-17 (2011).
Research Articles on WBP2
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Products associated with anti-WBP2 antibody
Diseases associated with anti-WBP2 antibody
Organs/Tissues associated with anti-WBP2 antibody
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