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anti-Hsp90 antibody :: Mouse Hsp90 Monoclonal Antibody

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Catalog # MBS190558
Unit / Price
  0.1 mg  /  $320 +1 FREE 8GB USB
anti-Hsp90 antibody
Product Name

Hsp90, Monoclonal Antibody

Popular Item
Full Product Name

Anti-Hsp90 Monoclonal Antibody

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
4F3.E8
Host
Mouse
Species Reactivity
Human, mouse, rat
Specificity
Hsp90
This antibody recognizes human, mouse, and rat Hsp90alpha and beta. Other species have not been tested.
Form/Format
100ug Protein G-purified antibody in PBS, pH 7.4.
Antigen
Recombinant human Hsp90 prufified from E.coli.
Preservative
None.
Dilution Instructions
Dilute in PBS or medium which is identical to that used in the assay system.
Preparation and Storage
This antibody is stable for at least one (1) year at -20 degree C. Avoid repeated freezing and thawing.
Other Notes
Small volumes of anti-Hsp90 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Hsp90 antibody
Hsp90 is an abundantly and ubiquitously expressed heat shock protein found in all eukaryotic cells. It exists in two principal forms, alpha and beta, which share 85% sequence homology. Both forms are expressed in the cytosol. Hsp90alpha exists primarily as a homodimer while Hsp90beta exists mainly as a monomer. Hsp90 plays a role in folding, assembly, maturation, and stabilization of specific proteins as a key component of a chaperone complex. Most of the Hsp90-regulated proteins that have been identified are involved in cell signaling; kinases, v-Src, Wee1, c-Raf, and p53 are some examples. When bound to ATP, Hsp90 interacts with cochaperones Cdc37, p23, and various immunophilin-like proteins to form complexes that stabilize and protect target proteins from proteasomal degradation.
Applications Tested/Suitable for anti-Hsp90 antibody
ELISA; Immunoprecipitation; Immunohistochemistry; Immunocytochemistry; Immunoblotting
Application Notes for anti-Hsp90 antibody
Immunoblotting: use at 0.5-1ug/ml. A band of ~90 kDa is detected. ELISA Immunohistochemistry/ Immunocytochemistry Imunoprecipitation. User should determine optimal concentrations for their application. Positive control: Heat-shocked HeLa cell lysate.
NCBI/Uniprot data below describe general gene information for Hsp90. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Official Full Name
Hsp90
Protein Family
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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