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Rat anti-Mouse CD107a (LAMP-1) Monoclonal Antibody

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Catalog # MBS673717
Unit / Price
  0.5 mg  /  $290 +1 FREE 8GB USB
anti-CD107a (LAMP-1) antibody
Product Name

CD107a (LAMP-1), Monoclonal Antibody

Popular Item
Full Product Name

Rat Anti-Mouse CD107a/LAMP-1-UNLB

Product Synonym Names
Rat Anti-Mouse CD107a/LAMP-1 - Purified, Unlabeled Antibody; Rat Anti-Mouse CD107a (LAMP-1)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Rat (Sprague-Dawley) IgG2a kappa
Clone Number
Species Reactivity
Murine CD107a/LAMP-1 (Mr 110-140 kDa with a core protein of Mr ~40 kDa)
CD107a, also known as lysosomal-associated membrane protein 1 (LAMP-1), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles.^1 It is a ligand for galaptin, an S-type lectin present in extracellular matrix, through its recognition of acetyllactosamine oligosaccharide chains, and is a ligand for E-selectin-mediated cell adhesion.^2 CD107a is principally expressed in epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice.^3 LAMP-1 may function in protecting the inner surface of the lysosomal membrane by forming a barrier to lysosomal hydrolases.^4
Purified (UNLB) Antibody
Plasma membrane fraction of mouse embryo NIH3T3 cell line
To ensure lot-to-lot consistency, each batch of monoclonal antibody is tested by flow cytometry to conform to characteristics of a standard reference reagent.
Preparation and Storage
The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C.
The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The allophycocyanin (APC) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
Other Notes
Small volumes of anti-CD107a (LAMP-1) antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CD107a (LAMP-1) antibody
Flow Cytometry; Immunohistochemistry (Frozen Sections); Immunoprecipitation; Western Blot
Application Notes for anti-CD107a (LAMP-1) antibody
Flow Cytometry Suggested Dilution: <=1 ug/10^6 cells
Product References and Citations for anti-CD107a (LAMP-1) antibody
1. Chen, J.W., W. Pan, M.P. d'Souza and J.T. August. 1985. Arch. Biochem. Biophys. 239:574.
2. Arterburn, L.M., B.J. Earles, and J.T. August. 1990. J. Biol. Chem. 265:7419.
3. Chen, J.W., G.L. Chen, M.P. d'Souza, T.L. Murphy, and J.T. August. 1986. Biochem. Soc. Symp. 51:97.
4. Fukuda, M. 1991. J. Biol. Chem. 266:21327.
6. Rohrer, J., A. Schweizer, D. Russell, and S. Kornfeld. 1996. J. Cell. Biol. 132:565.

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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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