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anti-Ly6c1 antibody :: Rat anti-Mouse Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS Monoclonal Antibody

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Catalog # MBS605460
Unit / Price
  0.1 mg  /  $690 +1 FREE 8GB USB
anti-Ly6c1 antibody
Product Name

Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS (Ly6c1), Monoclonal Antibody

Full Product Name

Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS (Ly-6c)

Product Synonym Names
Anti -Lymphocyte antigen 6C2, MACROPHAGE PRECURSOR CELLS (Ly-6c)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 15; NC_000081.5 (74875443..74879260, complement). Location: 15 D3; 15 42.7 cM
3D Structure
ModBase 3D Structure for P09568
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
9G221
Host
Rat
Species Reactivity
Mouse
Specificity
Recognizes mouse macrophage precursor cells in the mid-stage of their development (late CFU-M, monoblasts and monocytes).
Purity/Purification
Affinity Purified
Purified
Form/Format
Supplied as a liquid in PBS, 0.1% BSA, 0.02% sodium azide.
Immunogen
Mouse macrophage cell lines
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-Ly6c1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-Ly6c1 antibody
The antigen is a 14kD surface protein which is very similar to Ly-6C and may be analogous to human CD59. It is inducible by IFN-alpha, IFN-beta and IFN-gamma. In tissue sections, the antigen is found on macrophage precursor subpopulations. In the bone marrow and hemopoietic islands of the lymphoid organs, and in the spleen. Activated macrophages in inflammatory tissues also express the related antigen. The monoclonal antibody also identifies activated macrophages in inflammatory tissues where the simultaneous use of the murine pan-macrophage marker BM8 (anti-F4/80) is recommended. In combination with an anti-mouse CD31/PECAM-1 antibody, can be used to evaluate the cellular composition in murine bone marrow (e.g. using flow cytometric analysis). Also detects a wide range of endothelial cells.
Applications Tested/Suitable for anti-Ly6c1 antibody
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-Ly6c1 antibody
Suitable for use in Flow Cytometry and Immunohistochemistry.
Dilution: Flow Cytometry: 1:50
Immunohistochemistry: 1:50
The antigen is glutaraldehyde (0.05%) and paraformaldehyde (1%) resistant.
NCBI/Uniprot data below describe general gene information for Ly6c1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
14,193 Da[Similar Products]
NCBI Official Full Name
lymphocyte antigen 6C2
NCBI Official Synonym Full Names
lymphocyte antigen 6 complex, locus C1
NCBI Official Symbol
Ly6c1  [Similar Products]
NCBI Official Synonym Symbols
Ly6c; Ly-6C; Ly6c2; Ly-6C1; AA682074; AA959465
  [Similar Products]
NCBI Protein Information
lymphocyte antigen 6C2; ly-6C2; Lymphocyte antigen Ly-6C; lymphocyte antigen 6 complex, locus C
UniProt Protein Name
Lymphocyte antigen 6C1
Protein Family
UniProt Gene Name
Ly6c1  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
LY6C1_MOUSE
UniProt Comments for Ly6c1
LY6C1:

Cellular Component: membrane; plasma membrane; external side of plasma membrane
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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