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anti-H2-D1 antibody :: Mouse anti-Mouse MHC Class 1, H-2Kb Monoclonal Antibody

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Catalog # MBS604512
Unit / Price
  0.25 mg  /  $545 +1 FREE 8GB USB
anti-H2-D1 antibody
Product Name

MHC Class 1, H-2Kb (H2-D1), Monoclonal Antibody

Also Known As

MHC Class 1, H-2Kb (MHC Class I H-2Kb, H-2 Class I Histocompatibility Antigen K-B alpha Chain, H-2K(B), H2-K1, H-2K, H2-K, H-2K(d), MGC7052, MGC184092)

Product Synonym Names
Anti -MHC Class 1, H-2Kb (MHC Class I H-2Kb, H-2 Class I Histocompatibility Antigen K-B alpha Chain, H-2K(B), H2-K1, H-2K, H2-K, H-2K(d), MGC7052, MGC184092)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 17; NC_000083.5 (35400039..35404442). Location: 17 B1; 17 19.09 cM
3D Structure
ModBase 3D Structure for O19453
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
AF6-88.5
Host
Mouse
Species Reactivity
Mouse
Specificity
Recognizes the mouse MHC Class I H-2Kb antigen. Does not cross react with other haplotypes.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Immunogen
Mouse MHC Class 1, H2, Kb
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Other Notes
Small volumes of anti-H2-D1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-H2-D1 antibody
The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the histocompatibility 2 (H-2) region. There are 3 major MHC class I proteins encoded by the H-2 which are H-2K, H-2L and H-2D. The H- 2K gene is part of the murine H-2 complex on chromosome 17 and there are a large number of variant alleles of this gene.
Product Categories/Family for anti-H2-D1 antibody
Applications Tested/Suitable for anti-H2-D1 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-H2-D1 antibody
Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation.
Dilution: Flow Cytometry: 1:10-1:20. Use 10ul to label 10e6 cells in 100ul.
Immunohistochemistry: Frozen
Optimal working dilutions to be determined by researcher.
NCBI/Uniprot data below describe general gene information for H2-D1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,970 Da[Similar Products]
NCBI Official Full Name
MHC class I H2 antigen
NCBI Official Synonym Full Names
histocompatibility 2, D region locus 1
NCBI Official Symbol
H2-D1  [Similar Products]
NCBI Official Synonym Symbols
H-2D; H2-D
  [Similar Products]
NCBI Protein Information
H-2 class I histocompatibility antigen, L-D alpha chain; Q5k protein; MHC class I H-2Dp; MHC H2-D-q alpha-chain; MHC class I H2 antigen; H-2D cell surface glycoprotein; H2-DC1-beta transplantation antigen protein
UniProt Protein Name
Cell surface glycoprotein
UniProt Gene Name
H2-D1  [Similar Products]
UniProt Synonym Gene Names
H-2L(q)  [Similar Products]
UniProt Entry Name
O19453_MOUSE
UniProt Comments for H2-D1
KLC2: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. Belongs to the kinesin light chain family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Microtubule-binding; Motor

Cellular Component: ciliary rootlet; microtubule; kinesin complex; neuron projection; cytoskeleton; protein complex; membrane; cell; cytoplasm; intracellular; cytosol

Molecular Function: protein binding; kinesin binding; microtubule motor activity

Biological Process: axon cargo transport; microtubule-based movement
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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