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Hamster anti-Mouse TCR, alpha, beta Monoclonal Antibody

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Catalog # MBS632111
Unit / Price
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  0.1 mg  /  $355 +1 FREE 8GB USB
anti-TCR, alpha, beta antibody
Product Name

TCR, alpha, beta, Monoclonal Antibody

Full Product Name

TCR, alpha, beta (T Cell Receptor, T-cell Receptor beta-1 Chain C Region, TRBC1, T-cell Receptor alpha Chain C Region, TRAC, TCRA) (FITC)

Product Synonym Names
Anti -TCR, alpha, beta (T Cell Receptor, T-cell Receptor beta-1 Chain C Region, TRBC1, T-cell Receptor alpha Chain C Region, TRAC, TCRA) (FITC)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Clonality
Monoclonal
Isotype
IgG
Clone Number
H57-597
Host
Hamster
Species Reactivity
Mouse
Specificity
Recognizes common epitope of the beta chain of the mouse alpha/beta T cell receptor (TCR) complex. Does not react with gamma, delta TCR-bearing cells.
Purity/Purification
Purified
Purified
Form/Format
Supplied as a liquid in PBS, 0.1% sodium azide. Conjugated to FITC.
Immunogen
TCR affinity purified from mouse T-cell hybridoma DO-11.10
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degree C or colder. Aliquots are stable for at least 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-TCR, alpha, beta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-TCR, alpha, beta antibody
The alpha/beta TCR is expressed on T lymphocytes of all mouse strains tested.2 Plate-bound or soluble antibody activates a/b TCR-bearing T cells.2 In vitro and in vivo, this antibody can induce immature thymocytes to undergo apoptosis.3,4 In vivo administration of this antibody has been shown to deplete a/b TCR-bearing cells to near completion and prevent graft rejection.5
Applications Tested/Suitable for anti-TCR, alpha, beta antibody
Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes for anti-TCR, alpha, beta antibody
Flow cytometry 2,6,7, , Immunohistochemistry (acetone-fixed, frozen sections and formalin-fixed, paraffin-embedded sections), , Immunoprecipitation 2,8, , In vitro stimulation of a/b TCR-expressing T cells 2, , In vitro and in vivo depletion of a/b TCR-bearing cells 9
Dilution: Flow Cytometry: 2ug/10e6 cells
NCBI/Uniprot data below describe general gene information for TCR, alpha, beta. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
NCBI Official Full Name
TCR, partial
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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