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anti-CD2 antibody :: Mouse anti-Rat CD2 Monoclonal Antibody

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Catalog # MBS520064
Unit / Price
  0.1 mg  /  $250 +1 FREE 8GB USB
  0.5 mg  /  $420 +1 FREE 8GB USB
Testing Data
Product Name

CD2, Monoclonal Antibody

Popular Item
Full Product Name

Anti-Rat CD2 Biotin (Clone OX-34) (mouse IgG2a)

Product Synonym Names
CD2 Biotin (Clone OX-34) (mouse IgG2a); Anti-Rat CD2 (LFA-2) Monoclonal Antibody
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 1; NC_000001.10 (117297057..117311851). Location: 1p13.1
OMIM
186990
3D Structure
ModBase 3D Structure for P06729
Clonality
Monoclonal
Isotype
Mouse IgG2a
Clone Number
OX-34
Host
Mouse
Species Reactivity
Rat
Specificity
CD2 (LFA-2) (Rat CD2 (LFA-2))
Form/Format
Biotin
Concentration
0.1 mg/ml (lot specific)
Immunogen
T Blasts prepared in mixed lymphocyte reactions with rat T helper cells against irradiated spleen
Donor
BALB/c spleen
Fusion Partner
NSO/1
Presentation
Biotin/FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
Preparation and Storage
For all formats, store at 4 degree C. DO NOT FREEZE PE conjugates. For long term storage (Purified, Biotin, FITC, No Azide), aliquot and freeze unused portion at -20 degree C in volumes appropriate for single usage. Avoid freeze/thaw cycles
Other Notes
Small volumes of anti-CD2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD2 antibody
biotin anti-rat CD2 (LFA-2) monoclonal antibody reacts with the 50 kDa surface glycoprotein LFA-2, designated as CD2. LFA-2 is the receptor for LFA-3. This antibody labels all peripheral T cells and most thymocytes but does not label B cells or peritoneal macrophages. It does not activate T cells (1,2,3). This clone is reported to work with frozen and paraffin sections (4).
Applications Tested/Suitable for anti-CD2 antibody
Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)

Testing Data of anti-CD2 antibody
anti-CD2 antibody Testing Data image
NCBI/Uniprot data below describe general gene information for CD2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
39,448 Da
NCBI Official Full Name
T-cell surface antigen CD2
NCBI Official Synonym Full Names
CD2 molecule
NCBI Official Symbol
NCBI Official Synonym Symbols
T11; SRBC; LFA-2
  [Similar Products]
NCBI Protein Information
T-cell surface antigen CD2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor
UniProt Protein Name
T-cell surface antigen CD2
UniProt Synonym Protein Names
Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
CD2_HUMAN
NCBI Summary for CD2
CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]
UniProt Comments for CD2
Function: CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.

Subunit structure: Interacts with CD2AP

By similarity. Interacts with PSTPIP1. Ref.11

Subcellular location: Membrane; Single-pass type I membrane protein.

Sequence similarities: Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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