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anti-PPARg antibody :: Mouse Peroxisome Proliferator Activated Receptor Gamma (PPARg) Monoclonal Antibody

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Catalog # MBS2090989
Unit / Price
  0.01 mg  /  $105 +1 FREE 8GB USB
  0.02 mg  /  $115 +1 FREE 8GB USB
  0.05 mg  /  $155 +1 FREE 8GB USB
  0.1 mg  /  $195 +1 FREE 8GB USB
  0.2 mg  /  $250 +1 FREE 8GB USB
  1 mg  /  $580 +1 FREE 8GB USB
anti-PPARg antibody
Product Name

Peroxisome Proliferator Activated Receptor Gamma (PPARg), Monoclonal Antibody

Also Known As

Biotin-Linked Monoclonal Antibody to Peroxisome Proliferator Activated Receptor Gamma (PPARg)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
477
OMIM
U79012 mRNA
Clonality
Monoclonal
Host
Mouse
Species Reactivity
Rat
Concentration
500ug/ml (lot specific)
Conjugation
Biotin
Immunogen
Gln311~Leu493
Other Notes
Small volumes of anti-PPARg antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-PPARg antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for PPARg. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
Molecular Weight
21,580 Da
NCBI Official Full Name
peroxisome proliferator activated receptor gamma
UniProt Protein Name
Peroxisome proliferator-activated receptor gamma
UniProt Synonym Protein Names
Nuclear receptor subfamily 1 group C member 3
UniProt Gene Name
PPARG  [Similar Products]
UniProt Synonym Gene Names
NR1C3; PPAR-gamma  [Similar Products]
UniProt Comments for PPARg
PPAR-gamma: a transcription factor, member of the nuclear hormone receptor superfamily. Receptor for hypolipidemic drugs and fatty acids. Preferentially expressed in adipocytes as well as in vascular smooth muscle cells and macrophage. Regulator of adipogenesis and lipid metabolism, modulates insulin sensitivity, cell proliferation and inflammation. Phosphorylated and inhibited by MAP kinase. Heterodimerizes with the retinoid X receptor. Interacts with NCOA6 coactivator, leading to a strong increase in transcription of target genes. Two splice-variant isoforms have been described.

Protein type: DNA-binding; Nuclear receptor

Chromosomal Location of Human Ortholog: 3p25.2

Cellular Component: cytosol; intracellular membrane-bound organelle; nucleoplasm; nucleus; perinuclear region of cytoplasm; protein complex; RNA polymerase II transcription factor complex

Molecular Function: activating transcription factor binding; alpha-actinin binding; arachidonic acid binding; chromatin binding; DBD domain binding; DNA binding; DNA binding transcription factor activity; double-stranded DNA binding; drug binding; enzyme binding; estrogen receptor binding; identical protein binding; LBD domain binding; ligand-dependent nuclear receptor activity; ligand-dependent nuclear receptor transcription coactivator activity; peptide binding; prostaglandin receptor activity; protein binding; protein C-terminus binding; protein heterodimerization activity; protein phosphatase binding; protein self-association; retinoid X receptor binding; sequence-specific DNA binding; steroid hormone receptor activity; transcription factor binding; transcription regulatory region DNA binding; zinc ion binding

Biological Process: activation of cysteine-type endopeptidase activity involved in apoptotic process; cell fate commitment; cell maturation; cellular response to hyperoxia; cellular response to insulin stimulus; cellular response to prostaglandin E stimulus; cellular response to retinoic acid; cellular response to vitamin E; epithelial cell differentiation; fatty acid oxidation; G-protein coupled receptor signaling pathway; glucose homeostasis; heart development; innate immune response; lipid homeostasis; lipid metabolic process; lipoprotein transport; long-chain fatty acid transport; low-density lipoprotein receptor biosynthetic process; macrophage derived foam cell differentiation; monocyte differentiation; negative regulation of acute inflammatory response; negative regulation of angiogenesis; negative regulation of blood vessel endothelial cell migration; negative regulation of cell growth; negative regulation of cholesterol storage; negative regulation of collagen biosynthetic process; negative regulation of macrophage derived foam cell differentiation; negative regulation of pancreatic stellate cell proliferation; negative regulation of receptor biosynthetic process; negative regulation of sequestering of triglyceride; negative regulation of smooth muscle cell proliferation; negative regulation of telomerase activity; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of vascular endothelial cell proliferation; organ regeneration; placenta development; positive regulation of DNA binding; positive regulation of fat cell differentiation; positive regulation of fatty acid oxidation; positive regulation of oligodendrocyte differentiation; positive regulation of phagocytosis, engulfment; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-templated; regulation of blood pressure; regulation of circadian rhythm; response to caffeine; response to cold; response to drug; response to estrogen; response to lipid; response to mechanical stimulus; response to metformin; response to nutrient; response to retinoic acid; response to starvation; response to vitamin A; rhythmic process; signal transduction; steroid hormone mediated signaling; transcription initiation from RNA polymerase II promoter; white fat cell differentiation

Disease: Carotid Intimal Medial Thickness 1; Diabetes Mellitus, Noninsulin-dependent; Lipodystrophy, Familial Partial, Type 3; Obesity
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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