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anti-MAST1 antibody :: Mouse anti-Rat Syntrophin-Associated Serine/Threonine Kinase 124 Monoclonal Antibody

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Catalog # MBS602053
Unit / Price
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  0.1 mg  /  $910 +1 FREE 8GB USB
anti-MAST1 antibody
Product Name

Syntrophin-Associated Serine/Threonine Kinase 124 (MAST1), Monoclonal Antibody

Full Product Name

Syntrophin-Associated Serine/Threonine Kinase 124 (SAST-124)

Product Synonym Names
Anti -Syntrophin-Associated Serine/Threonine Kinase 124 (SAST-124)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
chromosome: 19; Location: 19q11
3D Structure
ModBase 3D Structure for Q810W7
Clonality
Monoclonal
Isotype
IgG1
Clone Number
6A623
Host
Mouse
Species Reactivity
Rat
Specificity
Recognizes rat SAST-124.
Purity/Purification
Affinity Purified
Purified IgG
Form/Format
Supplied as a liquid in PBS, containing 0.02% sodium azide and 0.1% BSA.
Immunogen
Rat Syntrophin-Associated Serine/Threonine Kinase 124 (SAST-124)
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-MAST1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MAST1 antibody
Syntrophin-associated serine/threonine kinase-124 (SAST-124) is a signalling molecule belonging to the microtubule-associated serine/threonine kinases. They have a unique structural feature with a serine/threonine kinase domain and a postsynaptic density protein-95/discs large/zona occludens-1 domain. SAST-124 is a signalling protein that binds to syntrophin, an adaptor protein that connects signalling molecules to the dystrophin-associated protein complex. SAST-124 is expressed in neurons of the subventricular zone and granule cells of the olfactory bulb, Islands of Calleja, hippocampal dentate gyrus and cerebellum. SAST-124 is selectively expressed in the nuclei of neurons. SAST-124 has a role in transcriptional regulation in the adult stem cells and their progeny cells in brain. SAST-124 is also located in glia-like small cells of the corpus callosum and the trigeminal ganglion cells indicating a function other than transcriptional regulation.
Applications Tested/Suitable for anti-MAST1 antibody
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Application Notes for anti-MAST1 antibody
Suitable for use in Western Blot, Immunoprecipitation, and Immunohistochemistry.
Dilution: Western Blot: 1:10
Immunoprecipitation: 1:10
Immunohistochemistry: frozen sections
NCBI/Uniprot data below describe general gene information for MAST1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
171,028 Da[Similar Products]
NCBI Official Full Name
syntrophin-associated serine/threonine kinase SAST124
NCBI Official Synonym Full Names
microtubule associated serine/threonine kinase 1
NCBI Official Symbol
MAST1  [Similar Products]
NCBI Official Synonym Symbols
Sast; MAST1
  [Similar Products]
NCBI Protein Information
microtubule-associated serine/threonine-protein kinase 1; syntrophin associated serine/threonine kinase; syntrophin-associated serine/threonine-protein kinase
UniProt Protein Name
Microtubule-associated serine/threonine-protein kinase 1
UniProt Synonym Protein Names
Syntrophin-associated serine/threonine-protein kinase
UniProt Gene Name
Mast1  [Similar Products]
UniProt Synonym Gene Names
UniProt Entry Name
MAST1_RAT
NCBI Summary for MAST1
interacts with syntrophin on the cell surface [RGD]
UniProt Comments for MAST1
MAST1: Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.

Protein type: EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, AGC; AGC group; MAST family

Cellular Component: cytoskeleton; membrane; cytoplasm; plasma membrane; nucleus

Molecular Function: protein serine/threonine kinase activity; magnesium ion binding; ATP binding

Biological Process: cytoskeleton organization and biogenesis; protein amino acid phosphorylation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Diseases associated with anti-MAST1 antibody
Organs/Tissues associated with anti-MAST1 antibody
 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with MAST1 and Brain
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