• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

anti-TIMP1 antibody :: Mouse anti-Rat Tissue Inhibitors Of Metalloproteinase 1 (TIMP1) Monoclonal Antibody

Scan QR to view Datasheet
Catalog # MBS2090897
Unit / Price
  0.01 mg  /  $105 +1 FREE 8GB USB
  0.02 mg  /  $115 +1 FREE 8GB USB
  0.05 mg  /  $155 +1 FREE 8GB USB
  0.1 mg  /  $195 +1 FREE 8GB USB
  0.2 mg  /  $250 +1 FREE 8GB USB
  1 mg  /  $580 +1 FREE 8GB USB
anti-TIMP1 antibody
Product Name

Tissue Inhibitors Of Metalloproteinase 1 (TIMP1), Monoclonal Antibody

Also Known As

Biotin-Linked Monoclonal Antibody to Tissue Inhibitors Of Metalloproteinase 1 (TIMP1)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
40
OMIM
X03124 mRNA
Clonality
Monoclonal
Host
Mouse
Species Reactivity
Rat
Concentration
500ug/ml (lot specific)
Conjugation
Biotin
Immunogen
Cys24~Ala217
Other Notes
Small volumes of anti-TIMP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-TIMP1 antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for TIMP1. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
23,171 Da
NCBI Official Full Name
tissue inhibitor of metalloproteinase 1, partial
NCBI Official Synonym Full Names
TIMP metallopeptidase inhibitor 1
NCBI Official Symbol
TIMP1  [Similar Products]
NCBI Official Synonym Symbols
EPA; EPO; HCI; CLGI; TIMP; TIMP-1
  [Similar Products]
NCBI Protein Information
metalloproteinase inhibitor 1
UniProt Protein Name
Metalloproteinase inhibitor 1
UniProt Synonym Protein Names
Erythroid-potentiating activity; EPA; Fibroblast collagenase inhibitor; Collagenase inhibitor; Tissue inhibitor of metalloproteinases 1; TIMP-1
UniProt Gene Name
TIMP1  [Similar Products]
UniProt Synonym Gene Names
CLGI; TIMP; EPA; Collagenase inhibitor; TIMP-1  [Similar Products]
NCBI Summary for TIMP1
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]
UniProt Comments for TIMP1
TIMP1: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16. Does not act on MMP-14. Belongs to the protease inhibitor I35 (TIMP) family.

Protein type: Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: Xp11.3

Cellular Component: basement membrane; endoplasmic reticulum lumen; extracellular region; extracellular space; proteinaceous extracellular matrix

Molecular Function: cytokine activity; growth factor activity; metalloendopeptidase inhibitor activity; protease binding; protein binding; zinc ion binding

Biological Process: aging; cartilage development; cell activation; cellular protein metabolic process; extracellular matrix disassembly; negative regulation of apoptosis; negative regulation of catalytic activity; negative regulation of membrane protein ectodomain proteolysis; platelet degranulation; positive regulation of cell proliferation; post-translational protein modification; response to cytokine; response to hormone; response to peptide hormone; wound healing
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000