P08101.2
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UniProt Primary Accession #
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UniProt Secondary Accession #
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NCBI Official Full Name
Low affinity immunoglobulin gamma Fc region receptor II
NCBI Official Synonym Full Names
Fc receptor, IgG, low affinity IIb
NCBI Official Synonym Symbols
CD32; Fcgr2; Fcr-2; Fcr-3; Ly-17; LyM-1; Lym-1; fcRII; FcgRII; Fcgr2a; Ly-m20; AI528646; Fc[g]RII; F630109E10Rik [Similar Products]
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-b; FcgammaRIIB; Fc-gamma-RII; fc-gamma RII; Fc gamma RIIB; fc-gamma-RIIB; fc gamma receptor IIB; lymphocyte antigen 17; igG Fc receptor II beta
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II
UniProt Synonym Protein Names
Fc gamma receptor IIB; Fc-gamma RII; Fc-gamma-RIIB; FcRII; IgG Fc receptor II beta; Lymphocyte antigen 17; Ly-17; CD_antigen: CD32
UniProt Synonym Gene Names
UniProt Entry Name
FCGR2_MOUSE
UniProt Comments for FCGR2B
FCGR2B: a transmembrane receptor for the Fc region of complexed or aggregated immunoglobulin gamma (IgG). Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down modulation of previous state of cell activation triggered via antigen receptors on B cells, T cells or via another Fc receptor. Three splice-variant isoforms have been observed.
Protein type: Cell surface; Membrane protein, integral; Oncoprotein
Cellular Component: recycling endosome; cytoskeleton; cell surface; membrane; integral to plasma membrane; cytoplasm; plasma membrane; integral to membrane; extracellular region; lipid raft; external side of plasma membrane
Molecular Function: protein binding; IgG binding; receptor signaling protein activity; immunoglobulin binding
Biological Process: negative regulation of phagocytosis; receptor-mediated endocytosis; negative regulation of interleukin-10 production; negative regulation of acute inflammatory response to antigenic stimulus; negative regulation of immune response; antigen processing and presentation of exogenous peptide antigen via MHC class II; defense response; negative regulation of B cell proliferation; endocytic recycling; negative regulation of type I hypersensitivity; mast cell activation; negative regulation of neutrophil apoptosis; negative regulation of humoral immune response mediated by circulating immunoglobulin; cell surface receptor linked signal transduction; response to bacterium; positive regulation of phagocytosis; negative regulation of immunoglobulin production; immune complex clearance; negative regulation of inflammatory response to antigenic stimulus; immune response; immunoglobulin mediated immune response; phagocytosis, engulfment
Research Articles on FCGR2B
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Pathways associated with FCGR2B elisa kit
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Organs/Tissues associated with FCGR2B elisa kit
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