NP_034646.1
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NCBI GenBank Nucleotide #
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UniProt Primary Accession #
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UniProt Related Accession #
Molecular Weight
41,709 Da
NCBI Official Full Name
protein CYR61
NCBI Official Synonym Full Names
cysteine rich protein 61
NCBI Protein Information
protein CYR61
UniProt Protein Name
Protein CYR61
UniProt Synonym Protein Names
3CH61; CCN family member 1; Cysteine-rich angiogenic inducer 61; Insulin-like growth factor-binding protein 10; IBP-10; IGF-binding protein 10; IGFBP-10
UniProt Synonym Gene Names
UniProt Comments for CYR61
Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5 (). CYR61-mediated gene regulation is dependent on heparin-binding (). Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1 (). Promotes cell adhesion and adhesive signaling through integrin alpha-6/beta-1, cell migration through integrin alpha-1/beta-5 and cell proliferation through integrin alpha-v/beta-3 ().
Research Articles on CYR61
Precautions
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Disclaimer
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Products associated with CYR61 rtu elisa kit
Pathways associated with CYR61 rtu elisa kit
Diseases associated with CYR61 rtu elisa kit
Organs/Tissues associated with CYR61 rtu elisa kit
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