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mS100b recombinant protein :: S100 Calcium Binding Protein B Recombinant Protein

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Catalog # MBS144086
Unit / Price
  0.005 mg  /  $140 +1 FREE 8GB USB
  0.025 mg  /  $205 +1 FREE 8GB USB
  1 mg  /  $2,235 +2 FREE 8GB USB
mS100b recombinant protein
Product Name

S100 Calcium Binding Protein B (mS100b), Recombinant Protein

Also Known As

Recombinant Mouse S100 Calcium Binding Protein B

Product Synonym Names
S100b Mouse; S100 Calcium Binding Protein B Mouse Recombinant; Protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B; Bpb; AI850290; MGC74317; S100b
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
92
Sequence
MGSSHHH HHH SSGLVPRGSH MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDEDGDGECD FQEFMAFVAM VTTACHEFFE HE
3D Structure
ModBase 3D Structure for P50114
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
S100B Mouse solution containing 20mM Tris-HCl pH-8, 1mM DTT & 10% glycerol.
Sterile filtered colorless solution.
Other Notes
Small volumes of mS100b recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
mS100b recombinant protein
Description: S100B Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 92 amino acids (1-112 a.a.) and having a molecular mass of 12.8 kDa. The Mouse S100B is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Introduction: S100B faintly binds calcium but binds zinc extremely strongly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. S100B binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction participates in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
NCBI/Uniprot data below describe general gene information for mS100b. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
10,728 Da
NCBI Official Full Name
protein S100-B
NCBI Official Synonym Full Names
S100 protein, beta polypeptide, neural
NCBI Official Symbol
S100b  [Similar Products]
NCBI Official Synonym Symbols
Bpb; AI850290
  [Similar Products]
NCBI Protein Information
protein S100-B; S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B
UniProt Protein Name
Protein S100-B
UniProt Synonym Protein Names
S-100 protein beta chain; S-100 protein subunit beta; S100 calcium-binding protein B
UniProt Gene Name
S100b  [Similar Products]
UniProt Entry Name
S100B_MOUSE
UniProt Comments for mS100b
S100B: Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Dimer of either two alpha chains, or two beta chains, or one alpha and one beta chain. The S100B dimer binds two molecules of STK38. Interacts with AGER. The S100B dimer interacts with two molecules of CAPZA1. Although predominant among the water-soluble brain proteins, S100 is also found in a variety of other tissues. Belongs to the S-101 family.

Protein type: Calcium-binding

Cellular Component: ruffle; extracellular space; intracellular membrane-bound organelle; cell soma; perinuclear region of cytoplasm; cytoplasm; extracellular region; nucleus

Molecular Function: identical protein binding; RAGE receptor binding; protein homodimerization activity; zinc ion binding; metal ion binding; calcium ion binding; calcium-dependent protein binding; receptor binding

Biological Process: regulation of long-term neuronal synaptic plasticity; cellular calcium ion homeostasis; regulation of cell shape; learning and/or memory; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of apoptosis; positive regulation of cell proliferation; energy reserve metabolic process; positive regulation of synaptic transmission; memory; regulation of cytokine biosynthetic process; regulation of neuronal synaptic plasticity
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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