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anti-MSN antibody :: Moesin/Ezrin/Radixin Antibody

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Catalog # MBS858824
Unit / Price
  0.1 mg  /  $215 +1 FREE 8GB USB
Product Name

Moesin/Ezrin/Radixin (MSN), Antibody

Popular Item
Also Known As

Moesin/Ezrin/Radixin (Ab-558) Antibody

Product Synonym Names
MOES; Membrane-organizing extension spike protein
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Length
577
OMIM
300988
3D Structure
ModBase 3D Structure for P26038
Species Reactivity
Human, Mouse, Rat
Specificity
Moesin/Ezrin/Radixin (Ab-558) antibody detects endogenous levels of total Moesin/Ezrin/Radixin protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human Moesin/Ezrin/Radixin around the phosphorylation site of threonine 558 (Y-K-TP-L-R).
Preparation and Storage
Store at-20 degree C for 1 year.
Other Notes
Small volumes of anti-MSN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-MSN antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-MSN antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000

Testing Data of anti-MSN antibody
Peptide-+
anti-MSN antibody Testing Data image
Immunohistochemistry (IHC) of anti-MSN antibody
Immunohistochemistry analysis of paraffin-embedded human pancreas tissue using Moesin/Ezrin/Radixin (Ab-558) antibody. Western blot analysis of extracts from NIH/3T3 cells, using Moesin/Ezrin/Radixin (Ab-558) antibody.
anti-MSN antibody Immunohistochemistry (IHC) (IHC) image
NCBI/Uniprot data below describe general gene information for MSN. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
67,820 Da
NCBI Official Full Name
moesin
NCBI Official Synonym Full Names
moesin
NCBI Official Symbol
NCBI Official Synonym Symbols
HEL70; IMD50
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NCBI Protein Information
moesin
UniProt Protein Name
Moesin
UniProt Synonym Protein Names
Membrane-organizing extension spike protein
Protein Family
UniProt Gene Name
NCBI Summary for MSN
Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement. [provided by RefSeq, Jul 2008]
UniProt Comments for MSN
Probably involved in connections of major cytoskeletal structures to the plasma membrane. May inhibit herpes simplex virus 1 infection at an early stage. Plays a role in regulating the proliferation, migration, and adhesion of human lymphoid cells and participates in immunologic synapse formation (PubMed:27405666).
Product References and Citations for anti-MSN antibody
Lankes W.T., Proc. Natl. Acad. Sci. U.S.A. 88:8297-8301(1991). Ross M.T., Nature 434:325-337(2005). Kim S.C., Mol. Cell 23:607-618(2006).

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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