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MYD88 recombinant protein

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Catalog # MBS5308835
Unit / Price
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  0.1 mg  /  $365 +1 FREE 8GB USB
SDS-Page
Product Name

MYD88, Recombinant Protein

Popular Item
Full Product Name

Purified recombinant Human MYD88 protein (His tag)

Product Synonym Names
MYD88 protein (His tag), MYD88D protein, MYD-88 protein, MYD 88 , MYD-88 , MYD88, MYD88 protein.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
1-316aa: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMRPD RAEAPGPPAM AAGGPGAGSA APVSSTSSLP LAALNMRVRR RLSLFLNVRT QVAADWTALA EEMDFEYLEI RQLETQADPT GRLLDAWQGR PGASVGRLLE LLTKLGRDDV LLELGPSIEE DCQKYILKQQ QEEAEKPLQV AAVDSSVPRT AELAGITTLD DPLGHMPERF DAFICYCPSD IQFVQEMIRQ LEQTNYRLKL CVSDRDVLPG TCVWSIASEL IEKRCRRMVV VVSDDYLQSK ECDFQTKFAL SLSPGAHQKR LIPIKYKAMK KEFPSILRFI TVCDYTNPCT KSWFWTRLAK ALSLP
Host
E.Coli
Purity/Purification
> 90% pure.
Form/Format
Supplied in liquid form in 20mM Tris-HCI buffer (pH 8.0) containing 0.4 urea, 10% glycerol.
Concentration
1 mg/ml (lot specific)
Protein Type
Recombinant
Species
Human
Tag/Conjugate
His Tag
Biohazard
Use standard laboratory precautions when handling this material.
Biological Significance
Myeloid differentiation primary response gene 88, also known as MYD88,acts via IRAK1, IRAK2, IRF7 and TRAF6, leading to NF-kappa-B activation, cytokyne secretion and the inflammatory response. This protein increases IL-8 transcription. It is involved in IL-18 mediated signaling pathway. MYD88 activated IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN-beta, NOS2/INOS, and IL12A genes.
Preparation and Storage
Store at 4°C for short term storage. Aliquot and store at -20°C for long term storage. Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of MYD88 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for MYD88 recombinant protein
Applications Tested/Suitable for MYD88 recombinant protein
SDS-PAGE

Figure annotation denotes ug of protein loaded and % gel used.
MYD88 recombinant protein SDS-Page image
NCBI/Uniprot data below describe general gene information for MYD88. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
Molecular Weight
38.7 kDa.
NCBI Official Full Name
MyD88
UniProt Protein Name
Myeloid differentiation primary response protein MyD88
UniProt Gene Name
MyD88  [Similar Products]
UniProt Comments for MYD88
Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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