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MYF6 peptide :: Herculin / MYF6 Peptide

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Catalog # MBS427273
Unit / Price
  0.1 mg  /  $190 +1 FREE 8GB USB
MYF6 peptide
Product Name

Herculin / MYF6, Peptide

Full Product Name

Herculin / MYF6 Immunizing Peptide

Product Synonym Names
MYF6; myogenic factor 6 (herculin); MRF4; bHLHc4; herculin; myogenic factor 6; myogenic factor-6; Herculin; Herculin / MYF6
Product Gene Name
Antibody/Peptide Pairs
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
C-SYRPKQEN LEGAD
OMIM
159991
Species Reactivity
Human, Mouse, Rat, Cow, Pig
Form/Format
100ug of dried peptide
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of MYF6 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for MYF6. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
26,953 Da
NCBI Official Full Name
myogenic factor 6
NCBI Official Synonym Full Names
myogenic factor 6
NCBI Official Symbol
NCBI Official Synonym Symbols
CNM3; MRF4; myf-6; bHLHc4
  [Similar Products]
NCBI Protein Information
myogenic factor 6
UniProt Protein Name
Myogenic factor 6
UniProt Synonym Protein Names
Class C basic helix-loop-helix protein 4; bHLHc4; Muscle-specific regulatory factor 4
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
BHLHC4; MRF4; Myf-6; bHLHc4  [Similar Products]
UniProt Entry Name
MYF6_HUMAN
NCBI Summary for MYF6
The protein encoded by this gene is a probable basic helix-loop-helix (bHLH) DNA binding protein involved in muscle differentiation. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of autosomal dominant centronuclear myopathy (ADCNM). [provided by RefSeq, May 2010]
UniProt Comments for MYF6
Myf-6: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein. Defects in MYF6 may be a cause of centronuclear myopathy type 3 (CNM3). A congenital muscle disorder characterized by progressive muscular weakness and wasting involving mainly limb girdle, trunk, and neck muscles. It may also affect distal muscles. Weakness may be present during childhood or adolescence or may not become evident until the third decade of life. Ptosis is a frequent clinical feature. The most prominent histopathologic features include high frequency of centrally located nuclei in muscle fibers not secondary to regeneration, radial arrangement of sarcoplasmic strands around the central nuclei, and predominance and hypotrophy of type 1 fibers.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 12q21

Cellular Component: nucleoplasm; nucleus

Molecular Function: protein heterodimerization activity; RNA polymerase II transcription factor activity, enhancer binding; transcription factor activity

Biological Process: muscle cell fate commitment; negative regulation of transcription, DNA-dependent; positive regulation of muscle cell differentiation; positive regulation of myoblast differentiation; positive regulation of skeletal muscle fiber development; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; skeletal muscle development; skeletal muscle regeneration; somitogenesis; transcription from RNA polymerase II promoter

Disease: Myopathy, Centronuclear, 3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Organs/Tissues associated with MYF6 peptide
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