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NAP3 elisa kit :: Rat Neutrophil Activating Protein 3 ELISA Kit

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Catalog # MBS103824
Unit / Price
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  48-Strip-Wells  /  $470 +1 FREE 8GB USB
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NAP3 elisa kit
Product Name

Neutrophil Activating Protein 3 (NAP3), ELISA Kit

Full Product Name

Rat Neutrophil Activating Protein 3 ELISA Kit

Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for P43313
Species Reactivity
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of NAP3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for NAP3purchase
MBS103824 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Neutrophil Activating Protein 3 (NAP3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NAP3. The ELISA analytical biochemical technique of the MBS103824 kit is based on NAP3 antibody-NAP3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NAP3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NAP3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for NAP3. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
16,933 Da
NCBI Official Full Name
neutrophil activating protein NapA
NCBI Official Symbol
HP0243  [Similar Products]
NCBI Protein Information
neutrophil activating protein NapA
UniProt Protein Name
DNA protection during starvation protein
UniProt Synonym Protein Names
Bacterioferritin; HP-NAP; Neutrophil-activating protein A
UniProt Gene Name
UniProt Synonym Gene Names
napA; NAP A  [Similar Products]
UniProt Entry Name
DPS_HELPY
UniProt Comments for NAP3
Function: Protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, which prevents hydroxyl radical production by the Fenton reaction

By similarity. Required for the survival in the presence of oxidative stress. Dps is also a virulence factor that activates neutrophils, mast cells and monocytes. It binds to neutrophil-glycosphingolipids and to sulfated carbohydrates on mucin. It might have a role in the accumulation of neutrophils and monocytes at the site of infection. Induces superoxide anion generation, adhesion and chemotaxis of neutrophils, through a pertussis toxin-sensitive pathway involving MAP kinases. Ref.2 Ref.11 Ref.14 Ref.15 Ref.16 Ref.17

Catalytic activity: 2 Fe2+ + H2O2 + 2 H+ = 2 Fe3+ + 2 H2O.

Subunit structure: Homododecamer. The 12 subunits form a hollow sphere into which the mineral iron core of up to 500 Fe3+ can be deposited. Ref.13 Ref.18

Subcellular location: Cytoplasm.

Domain: 12 di-nuclear ferroxidase centers are located at the interfaces between subunits related by 2-fold symmetry axes

By similarity.

Miscellaneous: According to Ref.16, colocalizes with DNA but according to Ref.12 it does not interact with DNA.

Sequence similarities: Belongs to the Dps family.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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