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NAPA recombinant protein :: Alpha-soluble NSF attachment protein (NAPA) Recombinant Protein

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Catalog # MBS965589
Unit / Price
  0.05 mg (E-Coli)  /  $700 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $810 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $945 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,030 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,040 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,095 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,240 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,280 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,505 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,560 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,960 +2 FREE 8GB USB
  1 mg (Yeast)  /  $1,970 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,085 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $3,040 +3 FREE 8GB USB
NAPA recombinant protein
Product Name

Alpha-soluble NSF attachment protein (NAPA), Recombinant Protein

Full Product Name

Recombinant Human Alpha-soluble NSF attachment protein (NAPA)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-295aa, Full length protein
Sequence
MDNSGKEAEA MALLAEAERK VKNSQSFFSG LFGGSSKIEE ACEIYARAAN MFKMAKNWSA AGNAFCQAAQ LHLQLQSKHD AATCFVDAGN AFKKADPQEA INCLMRAIEI YTDMGRFTIA AKHHISIAEI YETELVDIEK AIAHYEQSAD YYKGEESNSS ANKCLLKVAG YAALLEQYQK AIDIYEQVGT NAMDSPLLKY SAKDYFFKAA LCHFCIDMLN AKLAVQKYEE LFPAFSDSRE CKLMKKLLEA HEEQNVDSYT ESVKEYDSIS RLDQWLTTML LRIKKTIQGD EEDLR
OMIM
603215
3D Structure
ModBase 3D Structure for P54920
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Human
Storage Buffer
Tris-based buffer, 50% glycerol
Tag Information
Tag type will be determined during the manufacturing process
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of NAPA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
NAPA recombinant protein
The SNARE hypothesis is a model explaining the process of docking and fusion of vesicles to their target membranes. According to this model, membrane proteins from the vesicle (v-SNAREs) and proteins from the target membrane (t-SNAREs) govern the specificity of vesicle targeting and docking through mutual recognition. Once the 2 classes of SNAREs bind to each other, they form a complex that recruits the general elements of the fusion apparatus, namely NSF (N-ethylmaleimide-sensitive factor) and SNAPs (soluble NSF-attachment proteins), to the site of membrane fusion, thereby forming the 20S fusion complex. Alpha- and gamma-SNAP are found in a wide range of tissues and act synergistically in intra-Golgi transport. The sequence of the predicted 295-amino acid human protein encoded by NAPA shares 37%, 60%, and 67% identity with the sequences of yeast, Drosophila, and squid alpha-SNAP, respectively. Platelets contain some of the same proteins, including NSF, p115
TAP, alpha-SNAP, gamma-SNAP, and the t-SNAREs syntaxin-2 and syntaxin-4, that are used in many vesicular transport processes in other cell types. Platelet exocytosis uses a molecular mechanism similar to that used by other secretory cells, such as neurons, although the proteins used by the platelet and their modes of regulation may be quite different.
NCBI/Uniprot data below describe general gene information for NAPA. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,233 Da
NCBI Official Full Name
alpha-soluble NSF attachment protein
NCBI Official Synonym Full Names
NSF attachment protein alpha
NCBI Official Symbol
NCBI Official Synonym Symbols
SNAPA
  [Similar Products]
NCBI Protein Information
alpha-soluble NSF attachment protein
UniProt Protein Name
Alpha-soluble NSF attachment protein
UniProt Synonym Protein Names
N-ethylmaleimide-sensitive factor attachment protein alpha
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
SNAPA; SNAP-alpha  [Similar Products]
NCBI Summary for NAPA
This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. The encoded protein plays a role in the completion of membrane fusion by mediating the interaction of N-ethylmaleimide-sensitive factor (NSF) with the vesicle-associated and membrane-associated SNAP receptor (SNARE) complex, and stimulating the ATPase activity of NSF. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jun 2011]
UniProt Comments for NAPA
Required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus (Probable). Together with GNA12 promotes CDH5 localization to plasma membrane (PubMed:15980433).
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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