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NAT2 recombinant protein :: Arylamine N-acetyltransferase 2 (NAT2) Recombinant Protein

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Catalog # MBS964533
Unit / Price
  0.01 mg (E-Coli)  /  $135 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $255 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $420 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $665 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $825 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $970 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $1,090 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,110 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,210 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,220 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,255 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,725 +2 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $1,760 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $1,835 +2 FREE 8GB USB
  1 mg (Yeast)  /  $1,905 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,345 +2 FREE 8GB USB
SDS-PAGE
Product Name

Arylamine N-acetyltransferase 2 (NAT2), Recombinant Protein

Also Known As

Recombinant Human Arylamine N-acetyltransferase 2 (NAT2)

Product Synonym Names
Arylamine N-acetyltransferase 2; EC=2.3.1.5; Arylamide acetylase 2; N-acetyltransferase type 2; NAT-2; Polymorphic arylamine N-acetyltransferase; PNAT
Product Synonym Gene Name
NAT2; AAC2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-290aa; Full Length
Sequence Length
290
Sequence
MDIEAYFERI GYKNSRNKLD LETLTDILEH QIRAVPFENL NMHCGQAMEL GLEAIFDHIV RRNRGGWCLQ VNQLLYWALT TIGFQTTMLG GYFYIPPVNK YSTGMVHLLL QVTIDGRNYI VDAGSGSSSQ MWQPLELISG KDQPQVPCIF CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE DFESMNTYLQ TSPTSSFITT SFCSLQTPEG VYCLVGFILT YRKFNYKDNT DLVEFKTLTE EEVEEVLKNI FKISLGRNLV PKPGDGSLTI
OMIM
612182
3D Structure
ModBase 3D Structure for P11245
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of NAT2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
NAT2 recombinant protein
Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens.
Product Categories/Family for NAT2 recombinant protein

NAT2 recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for NAT2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
33,542 Da
NCBI Official Full Name
arylamine N-acetyltransferase 2
NCBI Official Synonym Full Names
N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCBI Official Symbol
NCBI Official Synonym Symbols
AAC2; PNAT; NAT-2
  [Similar Products]
NCBI Protein Information
arylamine N-acetyltransferase 2; arylamide acetylase 2; N-acetyltransferase type 2
UniProt Protein Name
Arylamine N-acetyltransferase 2
UniProt Synonym Protein Names
Arylamide acetylase 2; N-acetyltransferase type 2; NAT-2; Polymorphic arylamine N-acetyltransferase; PNAT
UniProt Gene Name
UniProt Synonym Gene Names
AAC2; NAT-2; PNAT  [Similar Products]
UniProt Entry Name
ARY2_HUMAN
NCBI Summary for NAT2
This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2). [provided by RefSeq, Jul 2008]
UniProt Comments for NAT2
NAT2: Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. Belongs to the arylamine N-acetyltransferase family.

Protein type: Secondary Metabolites Metabolism - caffeine; Xenobiotic Metabolism - drug metabolism - other enzymes; Acetyltransferase; EC 2.3.1.5; Translation

Chromosomal Location of Human Ortholog: 8p22

Cellular Component: cytosol

Molecular Function: arylamine N-acetyltransferase activity

Biological Process: xenobiotic metabolic process

Disease: Acetylation, Slow
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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