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NAT8L elisa kit :: Human N-acetyltransferase 8-like (GCN5-related, putative) ELISA Kit

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Catalog # MBS9343002
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NAT8L elisa kit
Product Name

N-acetyltransferase 8-like (GCN5-related, putative) (NAT8L), ELISA Kit

Popular Item
Full Product Name

Human N-acetylaspartate synthetase, NAT8L ELISA Kit

Product Synonym Names
Human N-acetylaspartate synthetase (NAT8L) ELISA kit; CML3; FLJ37478; MGC117272; NAT8-LIKE; ; N-acetyltransferase 8-like (GCN5-related; putative)
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
OMIM
gene 614063
3D Structure
ModBase 3D Structure for Q8N9F0
Species Reactivity
Specificity
No significant cross-reactivity or interference between this analyte and analogues is observed.
Samples
Serum, Plasma and Tissue Homogenate
Assay Type
Sandwich
Detection Range
0.25 ng/ml - 8 ng/ml.
Sensitivity
0.1 ng/ml.
Intra-assay Precision
Intra-assay CV (%) is less than 15%.
Inter-assay Precision
Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of NAT8L elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for NAT8Lpurchase
MBS9343002 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the N-acetyltransferase 8-like (GCN5-related, putative) (NAT8L) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing NAT8L. The ELISA analytical biochemical technique of the MBS9343002 kit is based on NAT8L antibody-NAT8L antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect NAT8L antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, NAT8L. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Related Product Information for
NAT8L elisa kit
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of NAT8L (hereafter termed this analyte) in undiluted original Human serum, plasma and tissue homogenate samples.
NCBI/Uniprot data below describe general gene information for NAT8L. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
32,837 Da
NCBI Official Full Name
N-acetylaspartate synthetase
NCBI Official Synonym Full Names
N-acetyltransferase 8-like (GCN5-related, putative)
NCBI Official Symbol
NAT8L  [Similar Products]
NCBI Official Synonym Symbols
CML3; NACED; NAT8-LIKE
  [Similar Products]
NCBI Protein Information
N-acetylaspartate synthetase; NAA synthetase; camello-like protein 3
UniProt Protein Name
N-acetylaspartate synthetase
UniProt Synonym Protein Names
Camello-like protein 3; N-acetyltransferase 8-like protein
UniProt Gene Name
NAT8L  [Similar Products]
UniProt Synonym Gene Names
CML3; NAA synthetase  [Similar Products]
UniProt Entry Name
NAT8L_HUMAN
NCBI Summary for NAT8L
This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010]
UniProt Comments for NAT8L
NAT8L: Plays a role in the regulation of lipogenesis by producing N-acetylaspartate acid (NAA), a brain-specific metabolite. NAA occurs in high concentration in brain and its hydrolysis plays a significant part in the maintenance of intact white matter. Promotes dopamine uptake by regulating TNF-alpha expression. Attenuates methamphetamine-induced inhibition of dopamine uptake. Defects in NAT8L are the cause of N-acetylaspartate deficiency (NACED). A metabolic disorder resulting in truncal ataxia, marked developmental delay, seizures, and secondary microcephaly. Belongs to the camello family.

Protein type: Membrane protein, integral; Acetyltransferase; EC 2.3.1.17

Chromosomal Location of Human Ortholog: 4p16.3

Cellular Component: mitochondrion; mitochondrial membrane; cytoplasm; integral to membrane; rough endoplasmic reticulum membrane

Molecular Function: aspartate N-acetyltransferase activity

Biological Process: positive regulation of dopamine uptake; metabolic process

Disease: N-acetylaspartate Deficiency
Research Articles on NAT8L
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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