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Enfuvirtide T-20 Native Protein

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Catalog # MBS142931
Unit / Price
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  100 mg  /  $345 +1 FREE 8GB USB
  500 mg  /  $1,165 +1 FREE 8GB USB
  1 g  /  $1,720 +2 FREE 8GB USB
Enfuvirtide T-20 native protein
Product Name

Enfuvirtide T-20, Native Protein

Popular Item
Full Product Name

Enfuvirtide T-20

Product Synonym Names
Enfuvirtide; Enfuvirtide (T-20); Enfuvirtide
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
Greater than 98.0% as determined by Analysis by RP-HPLC
Form/Format
The protein (1mg/ml) was lyophilized with no additives.
Sterile Filtered White lyophilized (freeze-dried) powder.
Solubility
Enfuvirtide lyophilized powder is best dissolved in alkaline conditions such as sterile pyrogen free 0.1% NaOH, 1% Na2CO3 or disodium phenyl phosphate at a concentration of 0.1mg/ml-1mg/ml. Enfuvirtide is insoluble in water.
Preparation and Storage
Lyophilized Enfuvirtide although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Enfuvirtide should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Other Notes
Small volumes of Enfuvirtide T-20 native protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Enfuvirtide T-20 native protein
Description: Enfuvirtide has an amino acid sequence Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu-Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu-Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu-Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2, molecular formula of C204H301N51O64 and a molecular weight of 4492 Dalton.

Introduction: Enfuvirtide also called human immunodeficiency fusion inhibitor blocks HIV's ability to infect healthy CD4 cells. It can reduce the amount of HIV in the blood and increase the number of CD4 cells. Enfuvirtide operates by disrupting the HIV-1 molecular machinery at the final phase of fusion with the target cell, preventing uninfected cells from becoming infected. Enfuvirtide mimics components of the HIV-1 fusion apparatus and displace them, preventing normal fusion. HIV attaches to the host CD4+ cell receptor using the viral protein GP120; upon binding, GP120 deforms allowing the viral protein GP41 to insert itself into the host cell's plasma membrane. Entry inhibitors bind to GP41 preventing the formation of an entry pore for the capsid of the virus, keeping it out of the cell.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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