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NDuFS4 recombinant protein

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Catalog # MBS203329
Unit / Price
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  0.1 mg  /  $310 +1 FREE 8GB USB
  0.5 mg  /  $720 +1 FREE 8GB USB
SDS-Page
Product Name

NDuFS4, Recombinant Protein

Full Product Name

NDuFS4, 43-175aa, Human, E Coli

Product Synonym Names
NADH dehydrogenase (ubiquinone) Fe-S protein 4; AQDQ; NADH dehydrogenase (ubiquinone) Fe-S protein 4 CI 18 kDa; CI AQDQ; Complex I 18 kDa; Complex I AQDQ; mitochondrial respiratory chain complex I (18 KD subunit); NADH dehydrogenase; NADH ubiquinone oxidoreductase 18 kDa subunit.
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MAQDQTQDTQ LITVDEKLDI TTLTGVPEEH IKTRKVRIFV PARNNMQSGV NNTKKWKMEF DTRERWENPL MGWASTADPL SNMVLTFSTK EDAVSFAEKN GWSYDIEERK VPKPKSKSYG ANFSWNKRTR VSTK
OMIM
AF020351 mRNA
3D Structure
ModBase 3D Structure for O43181
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20 mM Tris-HCl Buffer (pH 8.0) containing 30% glycerol
Concentration
0.5 mg/ml (determined by Bradford assay) (lot specific)
Antigen Species
Human
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
Other Notes
Small volumes of NDuFS4 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
NDuFS4 recombinant protein
NDuFS4, also known as NADH dehydrogenase (ubiquinone) Fe-S protein 4, is an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), the first multi-subunit enzyme complex of the mitochondrial respiratory chain. Complex I plays a vital role in cellular ATP production, the primary source of energy for many crucial processes in living cells. It removes electrons from NADH and passes them by a series of different protein-coupled redox centers to the electron acceptor ubiquinone. Recombinant human NDuFS4 protein was expressed in E Coli and purified by using conventional chromatography.
Product Categories/Family for NDuFS4 recombinant protein
Applications Tested/Suitable for NDuFS4 recombinant protein
SDS-PAGE

NCBI/Uniprot data below describe general gene information for NDuFS4. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
Molecular Weight
15.5 kDa (134aa), confirmed by MALDI-TOF.
NCBI Official Full Name
NADH dehydrogenase
NCBI Official Synonym Full Names
NADH:ubiquinone oxidoreductase subunit S4
NCBI Official Symbol
NDUFS4  [Similar Products]
NCBI Official Synonym Symbols
AQDQ; CI-18; CI-AQDQ; CI-18 kDa
  [Similar Products]
NCBI Protein Information
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
UniProt Protein Name
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
UniProt Synonym Protein Names
Complex I-18 kDa; CI-18 kDa; Complex I-AQDQ; CI-AQDQ; NADH-ubiquinone oxidoreductase 18 kDa subunit
UniProt Gene Name
NDUFS4  [Similar Products]
UniProt Synonym Gene Names
CI-18 kDa; CI-AQDQ  [Similar Products]
NCBI Summary for NDuFS4
This gene encodes an nuclear-encoded accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I, or NADH:ubiquinone oxidoreductase). Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone. Mutations in this gene can cause mitochondrial complex I deficiencies such as Leigh syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
UniProt Comments for NDuFS4
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Product References and Citations for NDuFS4 recombinant protein
Choi WS., et al. (2008), Proc Natl Acad Sci u S A. 105 (39):15136-41.; De Rasmo D., et al. (2008). Cell Signal. 20 (5):989-97.;

Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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