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NFL recombinant protein :: Neurofilament light polypeptide Recombinant Protein

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Catalog # MBS9422422
Unit / Price
  0.01 mg  /  $230 +1 FREE 8GB USB
  0.05 mg  /  $290 +1 FREE 8GB USB
  0.1 mg  /  $455 +1 FREE 8GB USB
  0.2 mg  /  $705 +1 FREE 8GB USB
  0.5 mg  /  $1,145 +1 FREE 8GB USB
  1 mg  /  $1,800 +2 FREE 8GB USB
NFL recombinant protein
Product Name

Neurofilament light polypeptide (NFL), Recombinant Protein

Popular Item
Also Known As

Recombinant Mus musculus Neurofilament light polypeptide

Product Synonym Names
68 kDa neurofilament protein; Neurofilament triplet L protein
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
Full Length, 2-543aa
Sequence Length
543
Sequence
SSFGYDPYFS TSYKRRYVET PRVHISSVRS GYSTARSAYS SYSAPVSSSL SVRRSYSSSS GSLMPSLENL DLSQVAAISN DLKSIRTQEK AQLQDLNDRF ASFIERVHEL EQQNKVLEAE LLVLRQKHSE PSRFRALYEQ EIRDLRLAAE DATNEKQALQ GEREGLEETL RNLQARYEEE VLSREDAEGR LMEARKGADE AALARAELEK RIDSLMDEIA FLKKVHEEEI AELQAQIQYA QISVEMDVSS KPDLSAALKD IRAQYEKLAA KNMQNAEEWF KSRFTVLTES AAKNTDAVRA AKDEVSESRR LLKAKTLEIE ACRGMNEALE KQLQELEDKQ NADISAMQDT INKLENELRS TKSEMARYLK EYQDLLNVKM ALDIEIAAYR KLLEGEETRL SFTSVGSITS GYSQSSQVFG RSAYSGLQSS SYLMSARSFP AYYTSHVQEE QTEVEETIEA TKAEEAKDEP PSEGEAEEEE KEKEEGEEEE GAEEEEAAKD ESEDTKEEEE GGEGEEEDTK ESEEEEKKEE SAGEEQVAKK KD
3D Structure
ModBase 3D Structure for P08551
Host
Yeast
Species Reactivity
Mouse
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Target Name
NFL
Calculated MW
63.38 kD
Target Length
Full length-2-543
Tag Info
His-tag
Preparation and Storage
Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Other Notes
Small volumes of NFL recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
NFL recombinant protein
Recombinant protein

Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
NCBI/Uniprot data below describe general gene information for NFL. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
neurofilament light polypeptide
NCBI Official Synonym Full Names
neurofilament, light polypeptide
NCBI Official Symbol
NCBI Official Synonym Symbols
Nfl; NF-L; NF68; CMT2E; AI847934
  [Similar Products]
NCBI Protein Information
neurofilament light polypeptide
UniProt Protein Name
Neurofilament light polypeptide
UniProt Synonym Protein Names
68 kDa neurofilament protein; Neurofilament triplet L protein
UniProt Gene Name
UniProt Synonym Gene Names
Nf68; Nfl; NF-L  [Similar Products]
UniProt Comments for NFL
NFL: one of the three (L, M, and H) intermediate filament proteins that form neurofilaments. Neurofilaments are involved in the maintenance of neuronal caliber. NF-L is the most abundant of the three neurofilament proteins. Defects cause Charcot-Marie-Tooth disease type 1F (CMT1F).

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 14|14 D1

Cellular Component: axon; cytoplasm; growth cone; intermediate filament; myelin sheath; neurofilament; neuron projection; TSC1-TSC2 complex

Molecular Function: identical protein binding; phospholipase binding; protein binding; protein binding, bridging; protein C-terminus binding; protein domain specific binding; protein heterodimerization activity; structural constituent of cytoskeleton

Biological Process: anterograde axon cargo transport; axon regeneration in the peripheral nervous system; axon transport of mitochondrion; intermediate filament bundle assembly; intermediate filament organization; intermediate filament polymerization and/or depolymerization; locomotion; microtubule cytoskeleton organization and biogenesis; negative regulation of neuron apoptosis; neurite morphogenesis; neurofilament bundle assembly; neurofilament cytoskeleton organization and biogenesis; neuromuscular process controlling balance; positive regulation of axonogenesis; protein polymerization; regulation of axon diameter; retrograde axon cargo transport
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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