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NP recombinant protein :: Influenza A virus Nucleoprotein (NP) Recombinant Protein

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Catalog # MBS9423735
Unit / Price
  0.01 mg  /  $265 +1 FREE 8GB USB
  0.05 mg  /  $350 +1 FREE 8GB USB
  0.1 mg  /  $560 +1 FREE 8GB USB
  0.2 mg  /  $880 +1 FREE 8GB USB
  0.5 mg  /  $1,145 +1 FREE 8GB USB
  1 mg  /  $1,795 +2 FREE 8GB USB
SDS-PAGE
Product Name

Influenza A virus Nucleoprotein (NP), Recombinant Protein

Popular Item
Also Known As

Recombinant Influenza A virus Nucleoprotein (NP)

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
Full Length, 1-498aa
Sequence
MASQGTKRSY EQMETDGERQ NATEIRASVG KMIGGIGRFY IQMCTELKLS DYEGRLIQNS LTIERMVLSA FDE RRNKY LEEHPSAGKD PKKTGGPIYR RVNGKWMREL ILYDKEEIRR IWRQANNGDD ATAGLTHMMI WHSNLND A TYQRTRALVR TGMDPRMCSL MQGSTLPRRS GAAGAAVKGV GTMVMELVRM IKRGINDRNF WRGENGRKT RIAYERMCN ILKGKFQTAA QKAMMDQVRE SRNPGNAEFE DLTFLARSAL ILRGSVAHKS CLPACVYGPA VASG YDFE REGYSLVGID PFRLLQNSQV YSLIRPNENP AHKSQLVWMA CHSAAFEDLR VLSFIKGTKV LPRGKLSTR GVQIASNEN METMESSTLE LRSRYWAIRT RSGGNTNQQR ASAGQISIQP TFSVQRNLPF DRTTIMAAFN GNTE GRTS DMRTEIIRMM ESARPEDVSF QGRGVFELSD EKAASPIVPS FDMSNEGSYF FGDNAEEYDN
3D Structure
ModBase 3D Structure for P03466
Host
E Coli
Purity/Purification
Greater than 80% as determined by SDS-PAGE.
Form/Format
Tris-based buffer, 50% glycerol
Tag Info
N-terminal 6xHis-B2M-tagged
Target Species
Influenza A virus (strain A/Puerto Rico/8/1934 H1N1)
Preparation and Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20 degree C/-80 degree C. The shelf life of lyophilized form is 12 months at -20 degree C/-80 degree C.
Other Notes
Small volumes of NP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

NCBI/Uniprot data below describe general gene information for NP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
56.2kD
NCBI Official Full Name
nucleoprotein
NCBI Official Symbol
NCBI Protein Information
nucleoprotein
UniProt Protein Name
Nucleoprotein
UniProt Synonym Protein Names
Nucleocapsid protein
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Protein N  [Similar Products]
UniProt Comments for NP
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the host nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals that are responsible for the active RNP import into the nucleus through cellular importin alpha/beta pathway. Later in the infection, nclear export of RNPs are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that nucleoprotein binds directly host exportin-1/XPO1 and plays an active role in RNPs nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmasks nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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