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NP recombinant protein :: Nucleoprotein (NP) Recombinant Protein

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Catalog # MBS1150039
Unit / Price
  0.01 mg (E-Coli)  /  $110 +1 FREE 8GB USB
  0.05 mg (E-Coli)  /  $190 +1 FREE 8GB USB
  0.1 mg (E-Coli)  /  $285 +1 FREE 8GB USB
  0.2 mg (E-Coli)  /  $460 +1 FREE 8GB USB
  0.5 mg (E-Coli)  /  $750 +1 FREE 8GB USB
  0.05 mg (Yeast)  /  $995 +1 FREE 8GB USB
  0.05 mg (Baculovirus)  /  $1,125 +1 FREE 8GB USB
  1 mg (E-Coli)  /  $1,180 +1 FREE 8GB USB
  0.2 mg (Yeast)  /  $1,350 +1 FREE 8GB USB
  0.05 mg (Mammalian-Cell)  /  $1,375 +1 FREE 8GB USB
  0.1 mg (Baculovirus)  /  $1,430 +1 FREE 8GB USB
  0.5 mg (Yeast)  /  $1,525 +1 FREE 8GB USB
  0.5 mg (Baculovirus)  /  $2,045 +2 FREE 8GB USB
  0.1 mg (Mammalian-Cell)  /  $2,075 +2 FREE 8GB USB
  1 mg (Yeast)  /  $2,320 +2 FREE 8GB USB
  1 mg (Baculovirus)  /  $2,690 +3 FREE 8GB USB
SDS-PAGE
Product Name

Nucleoprotein (NP), Recombinant Protein

Popular Item
Also Known As

Recombinant Influenza A virus Nucleoprotein (NP)

Product Synonym Names
Nucleoprotein; Nucleocapsid protein; Protein N
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-498aa; Full Length
Sequence Length
498
Sequence
MASQGTKRSY EQMETGGERQ DATEIRASVG RMIGGIGRFY IQMCTELKLS DYEGRLIQNS ITIERMVLSA FDERRNKYLE EHPSAGKDPK KTGGPIYKRI DGKWMRELIL YDKEEIRRVW RQANNGEDAT AGLTHIMIWH SNLNDATYQR TRALVRTGMD PRMCSLMQGS TLPRRSGAAG AAVKGVGTIA MELIGMIKRG INDRNFWRGE NGRRTRIAYE RMCNILKGKF QTAAQRAMMD QVRESRNPGN AEIEDLIFLA RSALILRGSV AHKSCLPACV YGLAVASGHD FEREGYSLVG IDPFKLLQNS QVFSLIRPNE NPAHKSQLVW MACHSAAFED LRVSGFIRGK KVVPRGRLST RGVQIASNEN VEAMDSSTLE LRSRYWAIRT RSGGNTNQQK ASADQISVQP TFSVQRNLPF ERATVMAAFI GDNEGRTSDM RTEIIRMMES AKPEDLSFQG RGVFELSDEK ATNPIVPSFD MNNEGSYFFG DNAEEYDN
3D Structure
ModBase 3D Structure for P26074
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Influenza A virus (strain A/New Jersey/8/1976 H1N1)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 9001:2008 Certified Laboratory.
Other Notes
Small volumes of NP recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
NP recombinant protein
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus
Product Categories/Family for NP recombinant protein

NP recombinant protein SDS-PAGE image
(Note: Representative image, actual molecular weight may vary depending on Tag type and expression host)
NCBI/Uniprot data below describe general gene information for NP. It may not necessarily be applicable to this product.
NCBI GI #
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
Molecular Weight
56,005 Da
NCBI Official Full Name
Nucleoprotein
UniProt Protein Name
Nucleoprotein
UniProt Synonym Protein Names
Nucleocapsid protein; Protein N
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
Protein N  [Similar Products]
UniProt Entry Name
NCAP_I76A7
UniProt Comments for NP
Encapsidates the negative strand viral RNA, protecting it from nucleases. The encapsidated genomic RNA is termed the ribonucleoprotein (RNP) and serves as template for transcription and replication. The RNP needs to be localized in the nucleus to start an infectious cycle, but is too large to diffuse through the nuclear pore complex. NP comprises at least 2 nuclear localization signals and is responsible of the active RNP import into the nucleus through the cellular importin alpha/beta pathway. Later in the infection, nucleus export of RNP are mediated through viral proteins NEP interacting with M1 which binds nucleoproteins. It is possible that the nucleoprotein binds directly exportin-1 (XPO1) and plays an active role in RNP nuclear export. M1 interaction with RNP seems to hide nucleoprotein's nuclear localization signals. Soon after a virion infects a new cell, M1 dissociates from the RNP under acidification of the virion driven by M2 protein. Dissociation of M1 from RNP unmask nucleoprotein's nuclear localization signals, targeting the RNP to the nucleus ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Products associated withNP recombinant protein
 Reference Product  PubMed Publications
 FLNA recombinant protein  >12 publications with NP and FLNA
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