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NPY purified protein :: NEUROPEPTIDE Y Purified Protein

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Catalog # MBS230202
Unit / Price
  0.1 mg  /  $250 +1 FREE 8GB USB
NPY purified protein
Product Name

NEUROPEPTIDE Y (NPY), Purified Protein

Also Known As

SYNTHETIC HUMAN NEUROPEPTIDE Y

Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Length
97
Sequence
Y-P-S-K-P- D-N-P-G-E- D-A-P-A-E- D-M-A-R-Y- Y-S-A-L-R- H-Y-I-N-L- I-T-R-Q-R- Y-NH2
OMIM
162640
3D Structure
ModBase 3D Structure for P01303
Purity/Purification
HPLC: >97%
Form/Format
Purified
Purified synthetic peptide - liquid
Concentration
Total protein concentration 1.0mg/ml (lot specific)
Preparation
Synthetic peptide prepared by solid phase synthesis
Target Species
Human
Preparation and Storage
Store at -20 degree C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life: 18 months from date of despatch.
Other Notes
Small volumes of NPY purified protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for NPY purified protein
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for NPY. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
4271.8 amu[Similar Products]
NCBI Official Full Name
pro-neuropeptide Y preproprotein
NCBI Official Synonym Full Names
neuropeptide Y
NCBI Official Symbol
NCBI Official Synonym Symbols
NCBI Protein Information
pro-neuropeptide Y; prepro-neuropeptide Y
UniProt Protein Name
Pro-neuropeptide Y
UniProt Synonym Protein Names
Neuropeptide tyrosine; NPY
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
NPY; CPON  [Similar Products]
UniProt Entry Name
NPY_HUMAN
NCBI Summary for NPY
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. [provided by RefSeq, Oct 2014]
UniProt Comments for NPY
NPY: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. Belongs to the NPY family.

Protein type: Secreted, signal peptide; Secreted; Hormone

Chromosomal Location of Human Ortholog: 7p15.1

Cellular Component: Golgi apparatus; extracellular space; cell; extracellular region

Molecular Function: G-protein coupled receptor activity; neuropeptide hormone activity; neuropeptide Y receptor binding; calcium channel regulator activity; receptor binding

Biological Process: blood circulation; behavior; adult feeding behavior; synaptic transmission; G-protein signaling, coupled to cyclic nucleotide second messenger; cell proliferation; neuropeptide signaling pathway; calcium ion transport; regulation of blood pressure; positive regulation of appetite; digestion; regulation of appetite; feeding behavior; cerebral cortex development; cell motility; neurite development; central nervous system neuron development
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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